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Strength Training Response of Muscle in GLP-1 Users

Virginia Polytechnic Institute and State University · NCT07104539

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 50+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
30
US sites recruiting
1
Study start
October 8, 2025
Record last updated
January 21, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

GLP-1 medication is being prescribed for weight loss. However, GLP-1 medication may adversely affect muscle mass and muscle function. Moreover, any loss of muscle mass or muscle function with GLP-1 treatment may impair balance and increase fall risk. This is a particular concern among older adults already susceptible to the common muscle strength and muscle function loss with age, yet there is little evidence among this population. This study will address a gap in knowledge regarding the effects of GLP-1 treatment on muscle mass, muscle function, and balance/fall risk among adults age 50 and older.

Being studied: Strength Training; Wait first, then strength training

Conditions: Muscle Mass

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Age, 50y+
  • Be taking GLP-1 medicine (Weygovy or Zepbound) for 1 month or less
  • Weight \<300 lb
  • Pass a health and exercise readiness screening

Exclusion Criteria

  • Age \<50
  • Weight >300 lb
  • Osteoporosis
  • Active metabolic, neoplastic, or cardiovascular disease
  • Unable or unwilling to provide consent

Recruiting US locations

Study contacts (from the official record)

  • Kevin Davy · 540-231-3487 · kdavy@vt.edu
  • Elaina Marinik · 540-231-0923 · emarinik@vt.edu
All weight loss studies in Virginia →
Strength Training Response of Muscle in GLP-1 Users (NCT07104539) | Bored Studies