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Striated Esophageal Motor Function Modulation in Health and Disease

Medical College of Wisconsin · NCT05708885

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–90 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
557
US sites recruiting
1
Study start
September 13, 2022
Record last updated
May 5, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The investigators hypothesize that striated esophagus deglutitive motor function is modulated by pharyngeal phase swallowing biomechanics.

Being studied: Concurrent manometry/impedance and fluoroscopy with and without laryngeal restriction; Concurrent manometry/impedance and fluoroscopy before and after six weeks of using swallow muscle exercising device

Conditions: Dysphagia, Esophageal

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Healthy subjects aged 18 to 90 years.
  • Patents with dysphagia but normal high resolution esophageal manometric findings defined by the Chicago classification.

Exclusion Criteria

  • Anyone less than 18 years old.
  • Patients with recent head and neck cancer (\<1 month post-surgery or \<3 months post-chemo radiation.
  • Patients suffering from muscle diseases like muscular dystrophies, myopathies.
  • Patients with neuro-muscular junction disorders myasthenia gravis, Eaton-Lambert disorders.
  • Patients having history of allergy to lidocaine or barium.
  • Patients who are pregnant or lactating.
  • Patients who are medically unstable.
  • Patients who are unable to apply the exerciser independently or with the help of a caregiver.
  • Patients who lack cognition.

Recruiting US locations

  • Medical College of Wisconsin

    Milwaukee, WI 53086

    Site contact: Reza Shaker, MD · 4149556840 · rshaker@mcw.edu

Study contacts (from the official record)

  • Reza Shaker, MD · 4149556840 · rshaker@mcw.edu
  • Mark Kern · 4148053826 · mkern@mcw.edu
All healthy volunteers studies in Wisconsin →
Striated Esophageal Motor Function Modulation in Health and Disease (NCT05708885) | Bored Studies