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Studies of Dermatologic Diseases Biospecimen Acquisition Protocol

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) · NCT02471352

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 0 mo–100 · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
700
US sites recruiting
1
Study start
June 19, 2015
Record last updated
September 22, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Background

  • Skin disease can have many causes. It can have widespread consequences, and in rare cases can lead to death. Researchers want to determine the causes of various types of skin diseases and find a way to treat them.

Objectives

  • To determine the causes of various skin diseases and find ways to treat them.

Eligibility

  • People ages 2 and older who have:
  • A skin disease or at risk of developing a skin disease OR
  • A family member of persons with a skin disease
  • Healthy volunteers ages 2 and older

Design

  • Participants will be screened under a separate protocol.
  • Participants may take a survey about how their skin condition affects their quality of life.
  • Participants will have a medical history and a physical exam including a detailed skin exam. Pictures will be taken of their skin to document any skin disease.
  • Participants will have specimens collected. This may include:
  • Several teaspoons of blood taken at each visit
  • Stool samples
  • Nail and body fluid (like saliva) samples
  • Cheek swabs. The inside of the cheek will be scraped for about a minute in each direction to collect cells.
  • Collection of skin samples with:
  • A swab (like a Q-tip)
  • Gently scraping skin to remove the outer layers of cells
  • Applying and removing 1-inch pieces of tape
  • Participants may have up to 4 skin biopsies in 12 months, with 4 separate biopsies taken each time.
  • An area of skin will be numbed with an injection.
  • A piece of skin the size of a pencil eraser will be removed using a small instrument.
  • A flat scar usually develops at the biopsy site.

Conditions: Dermatologic Conditions; Healthy Volunteers; Normal Volunteers; Carcinoma, Merkel Cell

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria
  • INCLUSION CRITERIA:
  • Eligible participants must:
  • Have a dermatologic condition, as determined by the PI or AIs, OR --be at risk for developing a dermatologic condition, as determined by the PI or AIs, OR
  • be a family member of a person with a dermatologic condition OR
  • be a healthy volunteer, as defined as a person with no known significant health problems.
  • Be willing to provide biospecimens for research and clinical studies, and for storage to be used for future research.
  • Subjects of age greater than 0 years old (including only viable neonates) are eligible.

EXCLUSION CRITERIA

  • Presence of conditions that, in the judgment of the investigator, may put the subject at undue risk or make them unsuitable for participation in the study.
  • Inability to comply with the requirements of the protocol.

Recruiting US locations

  • National Institutes of Health Clinical Center

    Bethesda, MD 20892

    Site contact: Office of Patient Recruitment (OPR) · 800-411-2222 · ccopr@nih.gov

Study contacts (from the official record)

  • Heidi H Kong, M.D. · (301) 827-2460 · NIAMSderm@nih.gov
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Studies of Dermatologic Diseases Biospecimen Acquisition Protocol (NCT02471352) | Bored Studies