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Study to Investigate Vagus Nerve Stimulation to Augment Executive Function in Healthy and Cognitively Impaired Populations

University of Colorado, Denver · NCT07424365

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–65 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
80
US sites recruiting
1
Study start
May 19, 2025
Record last updated
February 20, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study plans to learn more about how stimulating the vagus nerve through gentle electrical stimulation applied to the ear can affect decision-making, problem-solving, and other thinking abilities. This process, called transcutaneous auricular vagus nerve stimulation (taVNS), could help improve brain function in both healthy individuals and people with Parkinson's disease (PD).

Being studied: transcutaneous auricular vagus nerve stimulation; sham stimulation

Conditions: Mild Cognitive Impairment (MCI); Parkinsons Disease (PD); Healthy Adult

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Individuals aged 18-65.
  • Ability to sign informed consent.
  • Ability to follow written and verbal instructions.
  • For the PD group, a clinical diagnosis of Parkinson's disease without severe motor or cognitive impairments.

Exclusion Criteria

  • Current uncontrolled and/or clinically significant medical condition.
  • Abnormal ear anatomy or active ear infection.
  • Electronic medical implants, such as pacemakers, cochlear prosthesis, neuro-stimulators.
  • Uncorrected visual impairments that would interfere with task performance.

(6) Other significant diseases or disorders that might impair study participation.

Recruiting US locations

  • Clinical Translational Research Center at CU Anschutz

    Aurora, CO 80045

    Site contact: Colorado Clinical and Translational Sciences Institute · 303-724-1222 · CCTSI.Helpdesk@ucdenver.edu

Study contacts (from the official record)

  • Elise R Carter · 3094335932 · elise.carter@cuanschutz.edu
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Study to Investigate Vagus Nerve Stimulation to Augment Executive… (NCT07424365) | Bored Studies