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Study to Understand Novel Biomarkers in Researching Dementia

Washington University School of Medicine · with National Institute on Aging (NIA) · NCT06547099

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 60+ · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
1800
US sites recruiting
1
Study start
August 14, 2024
Record last updated
September 11, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this study is to determine the relationships between amyloid, tau, and neurodegeneration biomarkers in the blood and the presence of Alzheimer's disease (AD) pathology, clinical cognitive decline, and diagnosis. We aim to understand how well blood-based biomarkers can diagnose and predict Alzheimer's disease, which will help to further develop and validate blood tests for the disease.

Being studied: Clinical tau PET; Clinical amyloid test; Research blood collection; Cognitive assessments

Conditions: Alzheimer Disease; Mild Cognitive Impairment; Dementia

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • At least 60 years of age
  • 80% of the newly enrolled clinic-based cohort will have symptoms of forgetfulness, mild cognitive impairment, mild dementia, or Alzheimer's disease as determined by their medical chart and/or provider
  • All SEABIRD participants will be invited to participate regardless of their cognitive status

Exclusion Criteria

  • Unable to perform one or more basic activities of daily living (eating, bathing, dressing, ambulating, toileting) due to cognitive impairment
  • Uncontrolled hepatitis B, hepatitis C, or HIV at time of blood collection
  • Taking a disease-modifying drug for AD at time of enrollment
  • Blood transfusion in the last three months
  • Unwilling or unable to participate in all study activities

Recruiting US locations

  • Washington University School of Medicine

    St Louis, MO 63110

    Site contact: Lisa Soke · 314-747-4857 · sunbirdstudy@wustl.edu

Study contacts (from the official record)

  • Lisa Soke · 314-747-4857 · sunbirdstudy@wustl.edu
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Study to Understand Novel Biomarkers in Researching Dementia (NCT06547099) | Bored Studies