SV2A in Older Adults
Yale University · with National Institute on Drug Abuse (NIDA) · NCT05465538
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 50+ · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Phase 1, Phase 2
- Target enrollment
- 24
- US sites recruiting
- 1
- Study start
- July 6, 2022
- Record last updated
- October 20, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
The aim of the study is to examine the effect of cannabis use on brain synaptic density among older adults using [11C]UCB-J PET imaging.
Being studied: [11C]UCB-J PET
Conditions: Cannabis Use
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Able to provide informed consent
- Male or female, aged ≥50 years
- No history of significant medical or neurological disease
- BMI ≤ 50
- If woman of childbearing potential, must agree to use an acceptable method of birth control, as determined by the principal investigator, for the duration of the study and up to one month after completion of PET scans
Exclusion Criteria
- Women with a positive pregnancy test or women who are lactating
- Have had exposure to ionizing radiation that in combination with the study tracer would result in a cumulative exposure that exceeds recommended exposure limits;
- History of a bleeding disorder or are currently taking anticoagulants
- Subjects who have donated blood within 8 weeks of the present study
Recruiting US locations
Conneticut Mental Health Center
New Haven, CT 06519
Site contact: Khaled Draghmeh, MD · 203-932-5711 · khaled.draghmeh@yale.edu
Study contacts (from the official record)
- Khaled Draghmeh, MD · 203-932-5711 · khaled.draghmeh@yale.edu
Similar studies in Connecticut
All healthy volunteers studies in Connecticut →- RecruitingHealthy volunteersPhase 1Overnight stay mentioned
A Study to Learn How Different Amounts of the Study Medicine Called PF-08103402 Are Tolerated and Act in the Body in Healthy Adults or Adults With Mild To-moderate Asthma
Pfizer
- Location
- New Haven, CT
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersEarly Phase 1Overnight stay mentioned
Investigating the Mu:Kappa Opioid Receptor Imbalance in Alcohol Use Disorder
Yale University
- Location
- New Haven, CT
- Eligibility basics
- Ages 21–70
- RecruitingHealthy volunteersPhase 1
MK-0947 PN-002: An Open-label Study to Evaluate Brain α-synuclein Deposition Using Positron Emission Tomography (PET) and [¹⁸F]MK-0947 in Participants With Parkinson's Disease (PD)
XingImaging, LLC
- Location
- New Haven, CT
- Eligibility basics
- Ages 40–80
- RecruitingHealthy volunteersEarly Phase 1
A Study of the Pharmacokinetics, Biodistribution and Dosimetry of Granzyme-B Targeted [Cu-64]-Labeled PET Radiotracers in Adult Healthy Volunteers
Ratio Therapeutics, Inc.
- Location
- New Haven, CT
- Eligibility basics
- Ages 18–60