The Effect of Vicia Faba Hydrolysate Supplementation on Muscle Strength Recovery
PepsiCo Global R&D · NCT06837298
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18–45 · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 76
- US sites recruiting
- 1
- Study start
- February 7, 2025
- Record last updated
- February 20, 2025
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
To investigate the effect of Vicia faba protein concentrate, a protein derived from Fava bean extract, on delayed onset muscle soreness (DOMS). Participants receive either 2.4g/day of PeptiStrong® supplement capsules or placebo capsules for 14 days until a strenuous exercise session. For the last 3 days, 2/3 of them stay on the same treatment and 1/3 of them switch from placebo to PeptiStrong®.
Being studied: Placebo control capsules; PeptiStrong® supplement capsules with same appearance as placebo capsules; PeptiStrong® supplement capsules following muscle damaging exercise on Day 14
Conditions: Muscle Damage; Muscle
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Males and females 18 - 45 years of age.
- Willing to fast overnight on the 4 testing occasions.
- Participants agree to abstain from taking additional supplements throughout the testing period, with particular emphasis placed upon protein-based products (e.g., whey or casein based protein powders; animal derived protein hydrolysates; natural supplements constituted of vegetative protein hydrolysates from rice, fava bean, pea, carrot, spirulina, broccoli, potatoes; marine derived secondary metabolite products or protein hydrolysates including Omega-3 capsules or DHA).
- Moderately active (exercise 3-5 days per week)
- Fluent in reading, writing, and speaking English
- Participants agree to maintain their normal diet and perform only light to moderate exercise for the duration of the study.
- BMI between 18.5 and 29.9 kg/m2
- Participants agree to refrain from consuming alcohol in the 48 hours leading up to a test day.
- Willingness to complete questionnaires, records and diaries associated with the study and to complete all lab visits.
- Refrain from any exercise from 48 hours prior to each test or blood draw.
- Healthy as determined by General Health Questionnaire.
- Non-smoker
Exclusion Criteria
- Individuals that are glucose-6-phosphate-dehydrogenase deficient. The test product in this study contains fava bean extract which may produce favism in genetically susceptible individuals.
- Alcohol or drug abuse in the past year.3. Testosterone or estrogen supplementation (not including women on oral contraceptives)
- Pregnant or nursing or planning to become pregnant.
- Participation in any other clinical trial in the past 30 days. Participation in any PepsiCo trial in the past 6 months
- Volunteers with unstable medical conditions.
- Any complaints that could interfere with the ability to exercise.
- Individuals who are cognitively impaired or unable to give informed consent.
- Any co-morbidities interacting with mobility or muscle metabolism of the lower limbs (e.g. arthritis, spasticity / rigidity, all neurological disorders, paralysis).
- Creatine supplements, corticosteroids, NSAIDS, amino acids, injectible peptides, collagen, and nicotinamide (Vit B3/niacin).
- Presence or history of neurological disorders or significant psychiatric illness.
- Any condition the study investigator believes would interfere with eligibility following the study protocol, effect the study results, or put the subject at undue risk.
- Participation in resistance or aerobic exercise within 48 hours of the test days.
- Participation of >3 high-intensity exercise sessions per week.
- Undertake recovery methods such as sea swims, foam rolling, cryotherapy or excessive stretching during days 14-17.
- Have been in contact with a suspected or confirmed case of COVID-19 in previous 14 days.
- Are Hepatitis A- or B-positive or have had a sexual partner infected with hepatitis or HIV and not taking medication.
- Are not employed by, or have a parent, guardian, or other immediate family member employed by a company that manufactures any products that compete with any Gatorade product. If you are unsure if a company would be considered a competitor to Gatorade, let the study investigator know the name of the other company and the nature of your relationship to that company before ou sign the informed consent
Recruiting US locations
Gatorade Sports Science Institute at IMG Academy
Bradenton, FL 34210
Site contact: Kris Osterberg, PhD, RD · 847-707-3118 · Kris.Osterberg@pepsico.com
Study contacts (from the official record)
- Kris Osterberg, PhD, RD · 847.707.3118 · kris.osterberg@pepsico.com
- Brandon Shepherd, MS · brandon.shepherd3@pepsico.com
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