Skip to content
Bored Studies
RecruitingAccepts healthy volunteers

The Prevalence of Neuropathic Pain Pathophysiology Associated With Ankle Fracture

Indiana University · NCT06420141

View Study & Apply (opens in a new tab)

Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–85 · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
250
US sites recruiting
1
Study start
January 3, 2024
Record last updated
June 26, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This application addresses the Peer Reviewed Medical Research Program Investigator-Initiated Research Award FY21 W81XWH-22-CPMRP-IIRA area of Chronic Pain Management Research Program- The investigators will utilize subjects who have sustained ankle fractures and may develop chronic pain following bone union. No attempt will be made to affect the experimental outcome in the subjects. This study will adhere to a core set of standards for rigorous study design and reporting to maximize the reproducibility and translational potential of research.

Conditions: Neuropathic Pain

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Fracture Group

Inclusion Criteria

  • 18-85 years old
  • an isolated rotational ankle (AO/OTA 44 types A-C) fracture that is treated operatively
  • Abbreviated Injury Scale \< 3 for non-extremity body systems
  • can speak, read, and understand English

Exclusion Criteria

  • treated for a chronic pain condition prior to their qualifying injury
  • on a pain contract
  • pathologic fracture
  • Daily use of gabapentin or opiods prior to enrollment

Control Group

Inclusion Criteria

  • 18-85 years of age
  • can speak, read, and understand English

Exclusion Criteria

  • Chronic pain or an ongoing acute pain condition
  • Currently or have previously sustained a bone fracture
  • Current Pain medication usage
  • Any previous orthopaedic surgical procedures
  • Must have been free of any surgeries for at least 5 years
  • Peripheral neuropathy
  • Individuals having had a major surgery or a major disease or condition, as determined by the PI, such as cardiovascular disease, metabolic disorders, renal disease, neurological disorders, or severe psychiatric conditions.

Recruiting US locations

  • Indiana University School of Medicine

    Indianapolis, IN 46202

    Site contact: Fletcher A White, PhD · 317-274-5164 · fawhite@iu.edu

Study contacts (from the official record)

  • Fletcher A White, PhD · 317-274-5264 · fawhite@iu.edu
  • Kelly Naugle, PhD · 317-274-5264 · kmnaugle@iu.edu
All neurology studies in Indiana →
The Prevalence of Neuropathic Pain Pathophysiology Associated With… (NCT06420141) | Bored Studies