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Training Upper Limbs of Neurodiverse Children by Connecting Brain Activities to a Virtual Reality Based Game

University of Nebraska · with Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institute of General Medical Sciences (NIGMS) · NCT06818877

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 6–17 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
51
US sites recruiting
1
Study start
July 30, 2025
Record last updated
September 3, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study is testing ways to help children with cerebral palsy (CP) improve how their hands work. Investigators want to see if brain activity using a virtual reality (VR) program can make their hands work better. The program is called Hand and Bimanual Intensive Therapy Virtual Reality (HABIT-VR). Investigators will compare how well HABIT-VR works to a simple VR program.

In the study a VR game will be played and participants in the treatment group, will have hand muscles gently stimulated to help the joints move.

Being studied: Brain-Computer Interface (BCI)-HABIT-VR; Hand and Bimanual Intensive Therapy Virtual Reality (HABIT-VR)

Conditions: Healthy Children; CP (Cerebral Palsy); CP; Cerebral Palsy

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Children with cerebral palsy
  • Aged 6 to 17
  • Unilateral and bilateral cerebral palsy (Hemiplegic or Diplegic cerebral palsy)
  • Manual Ability Classification System Score (MACS) between I-IV.
  • Gross Motor Function Classification System (GMFCS) levels ranging from I to III.
  • Ability to follow verbal instructions
  • Typically developing children
  • Aged 6 to 17
  • Good physical health
  • Ability to follow verbal instructions

Exclusion Criteria

  • Children with cerebral palsy
  • Other conditions leading to the inability to move the upper extremity or handle objects
  • Visual impairments preventing the performance of intervention and testing tasks
  • Received an intensive therapeutic intervention involving upper extremities, botulinum toxin in an upper extremity within the past 6 months, or any upper extremity surgery in the past year
  • Typically developing children
  • Chronic illnesses or medical conditions that could impact their development
  • Significant behavioral or emotional issues that could indicate developmental disorders or psychological conditions
  • Diagnosed developmental disorders [e.g., autism, Attention-deficit/hyperactivity disorder (ADHD), learning disabilities]

Recruiting US locations

  • University of Nebraska Medical Center, Munroe-Meyer Institute

    Omaha, NE 68106

    Site contact: Dr. Andrea Cunha, PT, PhD · 402-559-6219 · abaraldicunha@unmc.edu

Study contacts (from the official record)

  • Ahad Behboodi, PhD · 402-554-7525 · abehboodi@unomaha.edu
All healthy volunteers studies in Nebraska →
Training Upper Limbs of Neurodiverse Children by Connecting Brain… (NCT06818877) | Bored Studies