Transcranial Direct Current Stimulation and Extinction in Obsessive Compulsive Disorder

Inclusion Criteria

• All Participant Inclusion Criteria would include:

• 18 years of age or older
• speak English fluently, and
• able to provide written and verbal informed consent.
• Obsessive-compulsive disorder (OCD) Inclusion Criteria would include:

• meet criteria for OCD as determined by structured clinical interview
• exhibit significant current symptoms of OCD
• report duration of OCD symptoms of at least 1-year
• OCD symptoms are primary or co-primary relative to other psychiatric diagnoses
• stable psychiatric treatment (≥8-weeks) or no active treatment.
• exhibit significant current symptoms of OCD as determined by the Dimensional Obsessive-Compulsive Scale (DOCS) (≥18).

Exclusion Criteria

• All Participant Exclusion Criteria would include:

• active severe substance use disorder(s)
• acute suicidality
• history of bipolar or psychotic disorder(s)
• significant developmental disabilities
• loss of consciousness > 10 minutes
• history of traumatic brain injury
• major neurological disease
• a positive pregnancy test
• other brain stimulation or magnetic resonance imaging contraindications
• new psychological treatment within the past 8 weeks
• daily anxiolytic medication use (e.g., benzodiazepine).
• Non-Clinical Control Exclusion Criteria would include:

• meet current criteria for a psychiatric disorder as determined by structured clinical interview
• active-psychotropic medications.