Skip to content
Bored Studies
RecruitingAccepts healthy volunteers

Trial of Precision Medicine in Emergency Departments

University of Florida · with National Human Genome Research Institute (NHGRI) · NCT06448091

View Study & Apply (opens in a new tab)

Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 40+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
1200
US sites recruiting
2
Study start
March 18, 2025
Record last updated
June 10, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The objectives of this study are to (1) test the feasibility of the clinical implementation of preemptive pharmacogenetic (PGx) testing in the emergency department (ED) and (2) determine if PGx testing (with appropriate decision support) decreases ED return visits and hospitalizations. We will conduct a randomized, controlled, pragmatic clinical trial assessing both the real-world effectiveness as well as implementation outcomes using a targeted PGx testing panel in several UF Health EDs.

Being studied: Panel-based pharmacogenetic genotyping

Conditions: Pharmacogenomic Drug Interaction

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Adults 40 years or older presenting to a participating ED
  • Receipt of a new order/prescription for a selected PGx medication (Appendix 1), with a duration greater than 7 days, during the current ED visit or within 30 days prior.
  • Documentation of at least 2 prior ED or urgent care visits within the past 12 months

Exclusion Criteria

  • Prior clinical pharmacogenetic test results within the EHR for genes relevant for this study (Appendix 1).
  • History of hepatic or renal transplant
  • History of severe liver disease (stage Child-Pugh C) or renal disease eGFR \<15 ml/min.
  • Any medical condition that would prohibit the ability to complete the study
  • Prisoners, wards of the state, or patients being held under the Baker Act or Marchman Act
  • Life expectancy less than 6 months

Recruiting US locations

  • UF Health Jacksonville Downtown Emergency Department

    Jacksonville, FL 32209

    Site contact: Morgan Henson, MPH · 904-244-4234 · morgan.henson@jax.ufl.edu

  • UF Health Jacksonville North Emergency Department

    Jacksonville, FL 32218

    Site contact: Morgan Henson, MPH · 904-244-4234 · morgan.henson@jax.ufl.edu

Study contacts (from the official record)

  • Erica N Elwood, MHA · 3522736007 · erica.elwood@cop.ufl.edu
All healthy volunteers studies in Florida →