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RecruitingAccepts healthy volunteersEarly Phase 1

Type 1 Diabetes, Endothelin, and Skeletal Muscle Mitochondrial Dysfunction: The Role of Sirtuin-1

Augusta University · NCT04449198

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Early Phase 1
Target enrollment
24
US sites recruiting
1
Study start
October 14, 2020
Record last updated
January 28, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The proposed study is designed to test the hypothesis that treatment of resveratrol for 12 weeks will improve both endothelin-B receptor (aim 1) and skeletal muscle mitochondrial function (aim 2) in people with type 1 diabetes.

Being studied: Resveratrol; Placebo

Conditions: Type 1 Diabetes

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Men and premenopausal women
  • All races
  • Clinical diagnosis of insulin-dependent type 1 diabetes (patients only)

Exclusion Criteria

  • Clinical diagnosis of hepatic, cardiovascular, or renal disease
  • Uncontrolled diabetes (HbA1C >12%)
  • Diabetic complications (i.e. neuropathy)
  • Uncontrolled hypertension (>140/90 mm Hg on therapy)
  • Pregnancy
  • Use of vasoactive medications

Recruiting US locations

  • Augusta University/Georgia Prevention Institute/ Laboratory of Integrative and Exercise Physiology

    Augusta, GA 30912

    Site contact: Ryan Harris, PhD, CEP · 706-721-5998 · ryharris@augusta.edu

Study contacts (from the official record)

  • Ryan A Harris, PhD, CEP · 7067215998 · ryharris@augusta.edu
  • Jacob Looney, MS · 7067215483 · jlooney@augusta.edu
All diabetes studies in Georgia →
Type 1 Diabetes, Endothelin, and Skeletal Muscle Mitochondrial… (NCT04449198) | Bored Studies