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Understanding Metabolism and Inflammation Risks for Diabetes in Adolescents

University of Michigan · with National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · NCT06007404

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 14–18 · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
175
US sites recruiting
1
Study start
September 6, 2023
Record last updated
October 15, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This research study collects health-related information and blood samples to better understand how body composition, lifestyle habits, and diet influence meta-inflammatory monocytes (MiMos) in adolescents. The hypothesis of this study is that adolescents at risk for metabolic disease have enhanced MiMo related activities leading to insulin resistance.

Conditions: Type 2 Diabetes; Insulin Resistance; Obesity; Metabolic Disease; PreDiabetes

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Between 14 and 18 years of age
  • Tanner stage 4 or 5 (mature adult stage of puberty)
  • Normal weight (BMI ≥ 5th percentile \& \< 85th percentile), overweight (BMI > 86th percentile) \& \< 94th percentile), obese weight (BMI percentile ≥ 95th percentile), and/or pre-diabetes (HbA1c > 5.7%)
  • For Type 2 Diabetes cohort, diagnosis of Type 2 Diabetes

Exclusion Criteria

  • Currently pregnant
  • Use medications known to affect glucose metabolism (immunosuppressive medications, cancer medications, or high dose steroids), unless prescribed for Type 2 Diabetes management
  • Prior diagnosis of autoimmune disease, cancer, or a cognitive or perceptual disability that would inhibit following directions of study staff
  • Allergies or intolerance to milk, soy, or palm oil

Recruiting US locations

Study contacts (from the official record)

  • The Singer Lab Team · (734) 615-4938 · MiMoStudy@med.umich.edu
All weight loss studies in Michigan →
Understanding Metabolism and Inflammation Risks for Diabetes in… (NCT06007404) | Bored Studies