UPURS Trial for Patient-centered Management of Symptomatic Obstructing Stones
University of California, San Francisco · with University of Colorado, Denver · NCT05715086
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18+ · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 100
- US sites recruiting
- 1
- Study start
- September 6, 2023
- Record last updated
- September 15, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
A prospective, non-blinded, randomized controlled trial studying the management of symptomatic ureteral stones. This study will compare upfront ureteroscopy vs observation and delayed intervention for patients presenting to the emergency department with a symptomatic ureteral stone.
Being studied: Ureteroscopy
Conditions: Ureteral Stone
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Presenting to the Emergency Department (ED)
- Adult (> 18 yo)
- ≥5mm ureteral stone diagnosed on CT scan
- Presence of symptoms (pain, nausea, vomiting, hematuria)
Exclusion Criteria
- Strict indication for stent
- Stone burden not amenable to Ureteroscopy (URS)
- Dirty urine analysis (UA) or positive urine culture (UCx)
- Transplant kidney
- Presence of conduit
- Comorbidities not optimized for surgery
- Strong preference for surgery or observation
Recruiting US locations
University of Colorado
Aurora, CO 80045
Site contact: Heiko Yang, MD · HEIKO.YANG@CUANSCHUTZ.EDU
Study contacts (from the official record)
- Heiko Yang, MD · 720-848-1800 · HEIKO.YANG@CUANSCHUTZ.EDU
Similar studies in Colorado
All healthy volunteers studies in Colorado →- RecruitingHealthy volunteersPhase 1/Phase 2
A Study of BLB-201 RSV Vaccine in Infants and Children
Blue Lake Biotechnology Inc.
- Location
- Aurora, CO + 13 other US sites
- Eligibility basics
- Ages 6 mo–5
- RecruitingHealthy volunteersPhase 1
Study to Evaluate the Safety, Pharmacokinetic, and Pharmacodynamic Effects of MY006 in Healthy Volunteers and Patients With Peanut Allergy
Mabylon AG
- Location
- Aurora, CO + 7 other US sites
- Eligibility basics
- Ages 12–55
- RecruitingHealthy volunteersPhase 1
A Research Study Looking at How Different Doses of Study Medicine (Inno8) Work in the Body of People With Haemophilia A
Novo Nordisk A/S
- Location
- Aurora, CO + 4 other US sites
- Eligibility basics
- Ages 18–64 · Men only
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Novartis Pharmaceuticals
- Location
- Aurora, CO + 18 other US sites
- Eligibility basics
- Ages 18–100