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RecruitingAccepts healthy volunteersPhase 1/Phase 2

Use of Hyperpolarized Xenon Gas for Lung Imaging in Children and Adults

Children's Hospital Medical Center, Cincinnati · NCT02272049

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 6+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Phase 1, Phase 2
Target enrollment
300
US sites recruiting
1
Study start
December 2014
Record last updated
February 17, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this study is to evaluate the usefulness of hyperpolarized (HP) 129Xe (xenon) gas MRI for regional assessment of lung function in a normal population of children and adults and in adults and also in children with respiratory compromise due to a variety of diseases.

Being studied: Hyperpolarized 129 Xenon

Conditions: Respiratory Disorders

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Ages 6 and up
  • Participant must be able to hold breath for up to 16 seconds

Exclusion Criteria

  • History of heart defect
  • Pregnancy or positive pregnancy test
  • History of uncontrolled asthma defined for this study as requiring use of rescue inhaler ≥ 2 times in past month
  • Symptoms of respiratory infection (loose or productive cough or wheeze), chest tightness, or sinus infection within past week
  • Baseline oximetry at MRI visit of less than 95% on room air or less than 95% on a previously prescribed dosage of oxygen delivered by nasal cannula
  • Participant is claustrophobic and unable to tolerate the imaging.
  • Standard MRI exclusions (metal, implants)

Recruiting US locations

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, OH 45229

    Site contact: Jason C. Woods, PhD

Study contacts (from the official record)

  • Carrie Stevens, BS · 513-636-9973 · Carrie.Stevens@cchmc.org
  • Kelly Thornton, BS · 513-636-0604 · Kelly.Thornton@cchmc.org
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Use of Hyperpolarized Xenon Gas for Lung Imaging in Children and… (NCT02272049) | Bored Studies