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Vascular MRI Evaluation in Giant Cell Arteritis (VEGA)

University of Pennsylvania · with National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) · NCT05865054

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 50+ · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
400
US sites recruiting
2
Study start
July 29, 2020
Record last updated
September 25, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The research study is being conducted to determine the utility of magnetic resonance imaging (MRI) in identifying inflammation of arteries supplying blood to the head, brain, and eyes. The target population includes patient with suspected giant cell arteritis (GCA; temporal arteritis).

Being studied: Magnetic Resonance Imaging (MRI)

Conditions: Giant Cell Arteritis

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Age 50 years or older
  • First presentation of suspected GCA
  • New or worsening cranial manifestations within 4 weeks of enrollment concerning for active GCA
  • Elevated CRP greater than 1.0 mg/dl
  • Plan to undergo temporal artery biopsy or ultrasound for diagnosis

Exclusion Criteria

  • Contra-indication to receiving MRI including:

Implanted medical devices, pacemaker, and metallic foreign fragments inside body/orbits Known gadolinium allergy Women who are pregnant or nursing

  • Absence of cranial symptoms related to GCA (e.g., only large vessel GCA)

Recruiting US locations

  • Mayo Building and Gonda Building

    Rochester, MN 55905

    Site contact: Jennifer Sletten · 507-284-3695 · sletten.jennifer@mayo.edu

  • 3400 Civic Center Blvd

    Philadelphia, PA 19104

    Site contact: Brenda Hernandez-Romero, B.S · 917-548-2067 · Brenda_Hernandez-Romero@pennmedicine.upenn.edu

Study contacts (from the official record)

  • Brenda Hernandez-Romero, B.S · 917-548-2067 · Brenda_Hernandez-Romero@pennmedicine.upenn.edu
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Vascular MRI Evaluation in Giant Cell Arteritis (VEGA) (NCT05865054) | Bored Studies