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VEDA Study (DHEA vs Estradiol)

University of Arizona · NCT07574216

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 40–90 · Women only
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
324
US sites recruiting
1
Study start
August 4, 2026
Record last updated
September 21, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study is being done to compare two vaginal treatments, vaginal estrogen and vaginal DHEA, that are used to treat vaginal and urinary symptoms related to menopause. These symptoms may include vaginal dryness, discomfort, painful intercourse, or urinary problems and can affect quality of life and sexual health. Women who choose to participate will be randomly assigned to use one of the two treatments for a set period of time. Participants will complete questionnaires about their symptoms and sexual health and have simple vaginal testing at the beginning and end of the study. The goal of this research is to better understand how these treatments affect vaginal health and sexual function so healthcare providers can make informed treatment decisions and improve care for postmenopausal women.

Being studied: DHEA ovals; Estradiol 0.01% Vag Cream

Conditions: Post-menopause; Pre-menopause; Sexual Function; Menopause; Vaginal Dryness; Painful Intercourse

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Peri- or post-menopausal status
  • Presence of any genitourinary or vaginal symptom (e.g., dryness, itching, discomfort, dyspareunia)
  • Willingness and ability to use vaginal therapy
  • Ability to provide informed consent
  • English speaker
  • Ages 40-90

Exclusion Criteria

  • Use of systemic hormone therapy within the last 6 months
  • Gynecologic malignancy
  • Known allergy to study medications
  • Active vaginal infection at enrollment
  • Prior pelvic radiation

Recruiting US locations

  • Banner University Medical Center Phoenix

    Phoenix, AZ 85006

    Site contact: Iris Jaramillo · 602-827-2078 · iyjarami@arizona.edu

Study contacts (from the official record)

  • Iridian (Iris) Jaramillo, M.S. · 602-827-2078 · iyjaramillo@arizona.edu
  • Pamela C Garcia-Filion, MD · 602-827-2882 · pgarciafilion@arizona.edu
All women’s health studies in Arizona →
VEDA Study (DHEA vs Estradiol) (NCT07574216) | Bored Studies