Location · Orange, CA
Clinical trials in Orange, CA
139 recruiting studies have a site in Orange, and 18 of them accept healthy volunteers.
139 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 4
A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor
Neurocrine Biosciences
- Location
- Orange, CA + 18 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
HMBeacon: A Phase 2 Study to Evaluate ALN-6400 in Adult and Adolescent Female Patients With VWD and HMB
Alnylam Pharmaceuticals
- Location
- Orange, CA + 5 other US sites
- Eligibility basics
- Ages 16–45 · Women only
- RecruitingPhase 3
An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1)
Transcend Therapeutics
- Location
- Orange, CA + 36 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
Amgen
- Location
- Orange, CA + 117 other US sites
- Eligibility basics
- Ages 18–99
- RecruitingPhase 3
A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome
Epygenix
- Location
- Orange, CA + 16 other US sites
- Eligibility basics
- Ages 2+
- RecruitingPhase 3
A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)
Bristol-Myers Squibb
- Location
- Orange, CA + 39 other US sites
- Eligibility basics
- Ages 18–65
- Recruiting
DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein Thrombosis
Inari Medical
- Location
- Orange, CA + 32 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease
GlaxoSmithKline
- Location
- Orange, CA + 13 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Study to Find Out How Nusinersen is Processed in the Body When Given Through the ThecaFlex DRx™ System in Adult and Pediatric Participants With Spinal Muscular Atrophy (PIERRE-PK)
Biogen
- Location
- Orange, CA + 11 other US sites
- Eligibility basics
- Ages 3+
- RecruitingPhase 1/Phase 2
Study of CTO1681 for the Prevention and Treatment of CRS in Patients Receiving CAR T-Cell Therapy
CytoAgents, Inc.
- Location
- Orange, CA + 5 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease
Immunovant Sciences GmbH
- Location
- Orange, CA + 54 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy
Alcyone Therapeutics, Inc
- Location
- Orange, CA + 14 other US sites
- Eligibility basics
- Ages 3+
- RecruitingPhase 1/Phase 2
AAV Gene Therapy Clinical Study in Adult Classic PKU (PHEdom)
NGGT INC.
- Location
- Orange, CA + 4 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingPhase 3
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- Location
- Orange, CA + 7 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 2
Descartes-08 in Autoantibody Myositis
Cartesian Therapeutics
- Location
- Orange, CA + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder
AbbVie
- Location
- Orange, CA + 32 other US sites
- Eligibility basics
- Ages 18–65
- Recruiting
Early Feasibility Study of "HyperQureTM RDN System", Laparoscopic Renal Denervation Therapy, in Patients With Resistant Hypertension
DeepQure Inc.
- Location
- Orange, CA + 5 other US sites
- Eligibility basics
- Ages 22–80
- RecruitingPhase 1/Phase 2
A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)
Nkarta, Inc.
- Location
- Orange, CA + 14 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Evaluation of the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix Breast Reconstruction (ADORA) in Adult Participants
AbbVie
- Location
- Orange, CA + 14 other US sites
- Eligibility basics
- Ages 18+ · Women only
- RecruitingPhase 3
Study to Evaluate Safety and Efficacy of Different PANZYGA Dose Regimens in Pediatric Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) Patients
Octapharma
- Location
- Orange, CA + 5 other US sites
- Eligibility basics
- Ages 2–17
- RecruitingPhase 2
Safety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD)
CSL Behring
- Location
- Orange, CA + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease
BlueRock Therapeutics
- Location
- Orange, CA + 33 other US sites
- Eligibility basics
- Ages 45–75
- RecruitingPhase 3
A Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's Disease
Takeda
- Location
- Orange, CA + 2 other US sites
- Eligibility basics
- Ages 2–17
- Recruiting
ATLAS (AltaValve) Pivotal Trial
4C Medical Technologies, Inc.
- Location
- Orange, CA + 35 other US sites
- Eligibility basics
- Ages 18+