Location · California
Clinical trials recruiting in California
1898 recruiting studies have at least one site in California; 701 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,898 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
24 studies with pay posted
Exact amounts posted by the research company for each study. The button opens that study’s own page.
Pays up to
$32,450
Clinical Trial for People with Type 2 Diabetes (S-38170)
Altasciences · Cypress, CA
Two schedule options (up to $18,050 or up to $32,450), with multi-night stays and outpatient visits.
Ages 18+ · Male/Female
View study & apply (opens in a new tab)Opens Altasciences’s page for this exact study
Pays up to
$32,150
Clinical Trial for Healthy Adults with Overweight or Obesity (N-38160)
Altasciences · Cypress, CA
Two schedule options (up to $17,750 or up to $32,150), with multi-night stays and outpatient visits.
Ages 18+ · Male/Female
View study & apply (opens in a new tab)Opens Altasciences’s page for this exact study
Pays up to
$30,000
Clinical Trial for People Living with Type 2 Diabetes (S-36900)
Altasciences · Cypress, CA
Ages 18+ · Male/Female
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Pays up to
$26,700
Diabetes Type 2
CenExel · Anaheim, CA
Ages 18–70 · Male/Female
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Pays up to
$26,600
Healthy Volunteers Needed for a Clinical Trial (N-40600)
Altasciences · Cypress, CA
Ages 18–55 · Male/Female
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Pays up to
$25,725
Clinical Study for People with Type 2 Diabetes (S-40910)
Altasciences · Cypress, CA
Ages 18–64 · Male/Female
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Pays up to
$25,000
Research Study for Obesity (N-34300)
Altasciences · Cypress, CA
Ages 18+ · Male/Female
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Pays up to
$16,050
Healthy but Overweight Volunteers Needed (N-39610)
Altasciences · Cypress, CA
Ages 18–55 · Male/Female
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Pays up to
$10,000
Research Study for Insomnia (S-41000)
Altasciences · Cypress, CA
Ages 18+ · Male/Female
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Pays up to
$8,950
Clinical Research Study for Healthy Males (N-40700)
Altasciences · Cypress, CA
Ages 18–59 · Male
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Pays up to
$6,400
Overweight / Obesity
CenExel · Anaheim, CA
Ages 18–65 · Male/Female
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Pays up to
$5,500
Memory Loss Study
CenExel · Sherman Oaks, CA
Ages 50–90 · Male/Female
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Pays up to
$5,000
Schizophrenia Study
CenExel · Los Alamitos, CA
Ages 18–65 · Male/Female
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Pays up to
$4,275
Alzheimer’s Disease Study
CenExel · Los Alamitos, CA
Ages 50–80 · Male/Female
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Pays up to
$3,900
Multiple Sclerosis Study
CenExel · Los Alamitos, CA
Ages 18–55 · Male/Female
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Pays up to
$3,220
Diabetes Study
CenExel · Los Alamitos, CA
Ages 18+ · Male/Female
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Pays up to
$2,800
Celiac Disease
CenExel · Anaheim, CA
Ages 18–70 · Male/Female
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Pays up to
$2,400
Parkinson’s Disease Study
CenExel · Los Alamitos, CA
Ages 35–85 · Male/Female
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Pays up to
$2,000
Hernia Repair – Inguinal (Groin Area)
CenExel · Anaheim, CA
Ages 18+ · Male/Female
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Pays up to
$1,825
Bipolar Disorder Study
CenExel · Los Alamitos, CA
Ages 18–65 · Male/Female
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Pays up to
$1,725
Migraine Trials
CenExel · Sherman Oaks, CA
Ages 18+ · Male/Female
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Pays up to
$1,650
Depression Study
CenExel · Los Alamitos, CA
Ages 18+ · Male/Female
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Pays up to
$1,125
Social Anxiety Study
CenExel · Sherman Oaks, CA
Ages 18–65 · Male/Female
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Pays up to
$1,000
Major Depression Trials
CenExel · Sherman Oaks, CA
Ages 18–65 · Male/Female
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More recruiting studies (pay not posted)
- RecruitingHealthy volunteersPhase 1Overnight stay mentioned
A Study to Investigate the Relative Bioavailability and Safety of Different Oral Formulations of Elecoglipron in Healthy Participants
AstraZeneca
- Location
- Glendale, CA + 1 other US site
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1Overnight stay mentioned
A Phase I Study to Investigate the Pharmacokinetics and Safety of Capivasertib in Participants With Moderate Hepatic Impairment
AstraZeneca
- Location
- Rialto, CA + 1 other US site
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1Overnight stay mentioned
A Study to Learn How the Body Processes the Study Medicine PF-07328948 in People With Reduced Kidney Function
Pfizer
- Location
- Lake Forest, CA + 3 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1Overnight stay mentioned
Phase 1 Study of SBS-147 in Healthy Adults
Sparian Biosciences, Inc
- Location
- Cypress, CA
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study of BLB-201 RSV Vaccine in Infants and Children
Blue Lake Biotechnology Inc.
- Location
- La Mesa, CA + 13 other US sites
- Eligibility basics
- Ages 6 mo–5
- RecruitingHealthy volunteersPhase 1
A Study of V132 in Healthy Older Participants (V132-001)
Merck Sharp & Dohme LLC
- Location
- Anaheim, CA + 9 other US sites
- Eligibility basics
- Ages 50–75
- RecruitingHealthy volunteersPhase 1
A Study to Investigate Pharmacokinetics (PK), Safety, and Tolerability of VH4367310 in Healthy Adult Participants
ViiV Healthcare
- Location
- Glendale, CA + 1 other US site
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
Study of S-892216 Long-acting Injectable (LAI) in Healthy Adult Participants
Shionogi
- Location
- Cypress, CA
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
A Study of LY4006896 in Healthy Participants and Participants With Parkinson's Disease
Eli Lilly and Company
- Location
- Los Alamitos, CA + 7 other US sites
- Eligibility basics
- Ages 30–85
- RecruitingHealthy volunteersPhase 1/Phase 2
Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older
Sanofi
- Location
- Huntington Beach, CA + 49 other US sites
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteersPhase 1
A Study to Test How BI 1291583 is Taken up in the Blood of People With and Without Liver Problems
Boehringer Ingelheim
- Location
- Rialto, CA
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1
A Study to Investigate Safety, Tolerability, and Pharmacokinetics of AZD3974 in Healthy Participants
AstraZeneca
- Location
- Glendale, CA + 1 other US site
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD1043 in Healthy Adult Participants Living With Overweight and/or Obesity.
AstraZeneca
- Location
- Glendale, CA + 1 other US site
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
First-in-Human Trial to Assess REGN20423 in Healthy Adult Participants and Adult Participants With Atopic Dermatitis
Regeneron Pharmaceuticals
- Location
- West Hills, CA + 5 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)
Merck Sharp & Dohme LLC
- Location
- Madera, CA + 14 other US sites
- Eligibility basics
- Ages 2 mo–1
- RecruitingHealthy volunteersPhase 1
A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Orally Administered TIX100 in Healthy Subjects
TIXiMED, Inc.
- Location
- Chula Vista, CA
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 1/Phase 2
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
Xencor, Inc.
- Location
- Palo Alto, CA + 27 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1
A Study of BBT001 in Healthy Volunteers (HVs) and in Adult Patients With Atopic Dermatitis (AD)
Bambusa Therapeutics
- Location
- Irvine, CA + 2 other US sites
- Eligibility basics
- Ages 18–72
- RecruitingHealthy volunteersPhase 1
A Study to Investigate the Safety and Pharmacokinetics of Single- and Multiple-ascending Doses of AZD4916 in Healthy Volunteers
AstraZeneca
- Location
- Glendale, CA
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
A Study to Assess Safety, Tolerability, and How Single and Multiple Injections or Infusions of ABBV-313 Affects the Body of Adult Participants
AbbVie
- Location
- Anaheim, CA + 1 other US site
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
Safety and Drug Concentrations of REGN20934 in Adults With Overweight or Obesity
Regeneron Pharmaceuticals
- Location
- Glendale, CA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Study to Evaluate the Drug Levels, Absolute Bioavailability, Safety, Tolerability, and Immunogenicity of Single-Dose of BMS-986446 in Healthy Adults After Single-dose Administration, and Participants With Early…
Bristol-Myers Squibb
- Location
- Anaheim, CA
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1/Phase 2
Study to Assess Safety and Immunogenicity of an Egg-based H5N8 Influenza Vaccine at Multiple Dose Levels Adjuvanted With Matrix-M in Healthy Participants 18 Years of Age and Above.
Sanofi
- Location
- Rolling Hills Estates, CA + 15 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1/Phase 2
First-in-human Study of the Safety, Tolerability, Pharmacokinetics, and Food Effect of ACCG-2671
Aconcagua Bio, Inc. a wholly owned subsidiary of Structure Therapeutics
- Location
- Lake Forest, CA + 2 other US sites
- Eligibility basics
- Ages 25–75