Location · California
Clinical trials recruiting in California
1898 recruiting studies have at least one site in California; 701 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,898 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingHealthy volunteersPhase 1
A Study to Evaluate the Pharmacokinetics (PK) and Safety of a Single Dose of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Normal Hepatic Function and Participants With Hepatic Impairment
Insmed Incorporated
- Location
- Lake Forest, CA + 3 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 1
A Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of BCX17725
BioCryst Pharmaceuticals
- Location
- Palo Alto, CA + 4 other US sites
- Eligibility basics
- Ages 12–65
- RecruitingHealthy volunteersEarly Phase 1
Radiocaine Safety Study
Lutroo Imaging LLC
- Location
- Stanford, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1/Phase 2
Study of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta Virus
Gilead Sciences
- Location
- Anaheim, CA + 4 other US sites
- Eligibility basics
- Ages 18–69
- RecruitingHealthy volunteersPhase 1
A Single-Dose Study of MT-201 and Concomitant Infliximab in Healthy Participants
Mirador Therapeutics, Inc.
- Location
- San Diego, CA
- Eligibility basics
- Ages 19–55
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease
Bristol-Myers Squibb
- Location
- La Jolla, CA + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
A Research Study on How UBT251 Affects Levels of Midazolam, Caffeine and Warfarin in the Blood of Participants With Excess Body Weight
Novo Nordisk A/S
- Location
- Cypress, CA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4248 in Healthy Participants and Participants With Chronic Kidney Disease and Type 2 Diabetes and to Assess Home Measurements of…
AstraZeneca
- Location
- Glendale, CA + 3 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1
A Clinical Trial of MK-4082 in Healthy Participants (MK-4082-005)
Merck Sharp & Dohme LLC
- Location
- Anaheim, CA
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
A Trial Evaluating AMG 127 in Healthy Participants and Participants With Type 2 Diabetes Mellitus
Amgen
- Location
- Lake Forest, CA + 1 other US site
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1
A Study to Assess the Safety, Tolerability and How Single Ascending Doses of ABBV-859 Moves Through the Body of Healthy Adult Participants
AbbVie
- Location
- Anaheim, CA + 1 other US site
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Study to Learn How the Body Processes the Study Medicine PF-07328948 in People With and Without Reduced Liver Function
Pfizer
- Location
- Lake Forest, CA + 2 other US sites
- Eligibility basics
- Ages 18–74
- RecruitingHealthy volunteersPhase 1
FIH Study to Evaluate the Tolerability of PF-07832837 in Healthy Adults and Patients
Pfizer
- Location
- Anaheim, CA + 4 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Novartis Pharmaceuticals
- Location
- Orange, CA + 18 other US sites
- Eligibility basics
- Ages 18–100
- RecruitingHealthy volunteersPhase 1
Renal Impairment Study for Oral EC5026
EicOsis Human Health Inc.
- Location
- Sacramento, CA
- Eligibility basics
- Ages 55+
- RecruitingHealthy volunteersEarly Phase 1
Secretome Treatment for Facial Rejuvenation
Acorn Biolabs Inc.
- Location
- Newport Beach, CA
- Eligibility basics
- Ages 30–75
- RecruitingHealthy volunteersPhase 1
A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B or Factor VII…
Equilibra Bioscience LLC
- Location
- Los Angeles, CA + 6 other US sites
- Eligibility basics
- Ages 18–60
- RecruitingHealthy volunteersPhase 1
A Study to Assess How Intravenous and Subcutaneous Administrations of Risankizumab Moves Through the Body of Healthy Adult Participants
AbbVie
- Location
- Anaheim, CA + 1 other US site
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Study of LY4006895 in Healthy Participants With Early Symptomatic Alzheimer's Disease (AD)
Eli Lilly and Company
- Location
- Los Alamitos, CA + 5 other US sites
- Eligibility basics
- Ages 45–85
- RecruitingHealthy volunteersPhase 1
A Single Dose, Phase 1 Study of JADE101 in Healthy Japanese and Chinese Participants
Jade Biosciences, Inc.
- Location
- Glendale, CA
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1/Phase 2
A Phase 1/2a Study of DB-2304 in Healthy Adults and SLE/CLE Participants
DualityBio Inc.
- Location
- La Palma, CA + 4 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study of MET233 in Combination With MET097 in Individuals With Obesity or Overweight With or Without Diabetes
Pfizer
- Location
- Cypress, CA
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1
A Study to Learn About a Vaccine Against E Coli in Healthy Adults
Pfizer
- Location
- Anaheim, CA + 9 other US sites
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteersPhase 1
A 3-part Study of SYX-5219 in Healthy Volunteers and Participants With Atopic Dermatitis
Sitryx Therapeutics Ltd
- Location
- Fremont, CA + 5 other US sites
- Eligibility basics
- Ages 18–65