Pain · California
Pain studies in California
31 studies have at least one recruiting site in California. Pain research covers chronic back pain, fibromyalgia, nerve pain and short-term pain after procedures, testing medicines, devices and non-drug approaches.
31 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
1 study with pay posted
Exact amounts posted by the research company for each study. The button opens that study’s own page.
Pays up to
$2,000
Hernia Repair – Inguinal (Groin Area)
CenExel · Anaheim, CA
Ages 18+ · Male/Female
View study & apply (opens in a new tab)Opens CenExel’s page for this exact study
More recruiting studies (pay not posted)
- RecruitingHealthy volunteersPhase 1Overnight stay mentioned
Phase 1 Study of SBS-147 in Healthy Adults
Sparian Biosciences, Inc
- Location
- Cypress, CA
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersEarly Phase 1
Brain Mechanisms Supporting Cannabis-induced Pain Relief
University of California, San Diego
- Location
- La Jolla, CA
- Eligibility basics
- Ages 21–65
- RecruitingPhase 3
An Open-Label, Safety and Efficacy Study of Cebranopadol in Participants With Acute Pain With Surgical or Non-Surgical Origin
Adneuris Therapeutics, Inc.
- Location
- Riverside, CA + 14 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Efficacy and Safety of VER-01 in the Treatment of Participants With Chronic Painful Lumbosacral Radiculopathy
Vertanical GmbH
- Location
- Long Beach, CA + 22 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy
Vertex Pharmaceuticals Incorporated
- Location
- Fresno, CA + 57 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease
DiscGenics, Inc.
- Location
- San Diego, CA + 29 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
Eli Lilly and Company
- Location
- Fountain Valley, CA + 37 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
Eli Lilly and Company
- Location
- Palm Springs, CA + 34 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research Design
Axsome Therapeutics, Inc.
- Location
- Anaheim, CA + 48 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Chronic Low Back Pain
Eli Lilly and Company
- Location
- Riverside, CA + 31 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Osteoarthritis Pain
Eli Lilly and Company
- Location
- Palm Springs, CA + 35 other US sites
- Eligibility basics
- Ages 40+
- RecruitingPhase 2
A Study to Assess Safety and Tolerability of PCRX-201 in Subjects With Painful Osteoarthritis of the Knee
Pacira Pharmaceuticals, Inc
- Location
- Huntington Beach, CA + 2 other US sites
- Eligibility basics
- Ages 45–80
- RecruitingPhase 3
Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy
Vertex Pharmaceuticals Incorporated
- Location
- Canoga Park, CA + 69 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Diabetic Peripheral Neuropathic Pain
Eli Lilly and Company
- Location
- Palm Springs, CA + 35 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
NT-II™ Collagen for Joint Discomfort and Function
Hofseth Biocare ASA
- Location
- San Francisco, CA
- Eligibility basics
- Ages 20–65
- RecruitingPhase 1
Safety and PK of Intrathecal CNTX-3001 for Intractable Chronic Low Back Pain
Centrexion Therapeutics
- Location
- Napa, CA
- Eligibility basics
- Ages 18–75
- Recruiting
Post Marketing Study of MagnetOs Easypack Putty Standalone Compared to Demineralized Bone Matrix or Fibers Mixed With Autograft in Patients Undergoing Posterolateral Lumbar Fusion
Kuros Biosurgery AG
- Location
- Irvine, CA + 5 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Freedom-1 Study for Chronic Knee Pain
Curonix LLC
- Location
- Placentia, CA + 12 other US sites
- Eligibility basics
- Ages 18+
- RecruitingEarly Phase 1
Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Knee Osteoarthritis
R3 Medical Research
- Location
- Beverly Hills, CA + 4 other US sites
- Eligibility basics
- Ages 30+
- RecruitingPhase 1
Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Lumbar Pain
R3 Stem Cell
- Location
- Beverly Hills, CA + 3 other US sites
- Eligibility basics
- Ages 20+
- RecruitingHealthy volunteersPhase 4
Bupivacaine With Epinephrine Over Diaphragm in Laparoscopy
Cedars-Sinai Medical Center
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 18+ · Women only
- RecruitingHealthy volunteers
Latinx Children and Surgery
University of California, Irvine
- Location
- Orange, CA
- Eligibility basics
- Ages 2–12
- RecruitingHealthy volunteers
Aromatherapy and Its Impact on Preoperative Anxiety, Postoperative Pain, and Patient Experience
Kaiser Permanente
- Location
- Stockton, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Blood Flow Restriction Training as a Targeted Intervention for Rowers With Back Pain.
Loma Linda University
- Location
- Loma Linda, CA
- Eligibility basics
- Ages 13–20
Who these studies look for
Studies usually set a pain score range and limits on pain medicines. Some short-term pain studies involve a scheduled minor procedure.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
What is an acute pain study?
Some studies measure pain relief after a planned minor procedure, such as dental surgery or bunion removal, performed as part of the study. Each listing describes what is involved.