Arthritis · California
Arthritis studies in California
45 studies have at least one recruiting site in California. Arthritis studies include osteoarthritis, rheumatoid arthritis, psoriatic arthritis, gout and ankylosing spondylitis.
45 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersEarly Phase 1
Biologic Therapy to Prevent Osteoarthritis After ACL Injury
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 18–35
- RecruitingPhase 2
A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)
Merck Sharp & Dohme LLC
- Location
- Fullerton, CA + 35 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis
Medipost, Inc.
- Location
- El Cajon, CA + 33 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions and Subcutaneous Injections of ABBV-519 in Adult Participants With Systemic Lupus Erythematosus (SLE) or…
AbbVie
- Location
- Tustin, CA + 11 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.
AstraZeneca
- Location
- La Jolla, CA + 2 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With…
Amgen
- Location
- Anaheim, CA + 73 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safey of PTP-001 (MOTYS™) in Knee Osteoarthritis Patients (MOTION-P)
Doron Therapeutics Inc.
- Location
- La Mesa, CA + 7 other US sites
- Eligibility basics
- Ages 40–80
- RecruitingPhase 3
A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have Not Taken Biologic Medicines
Takeda
- Location
- Fountain Valley, CA + 45 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability up to 6 Years of Intravenous (i.v.) Secukinumab in Pediatric Participants With Juvenile Psoriatic Arthritis (JPsA).
Novartis Pharmaceuticals
- Location
- Loma Linda, CA + 10 other US sites
- Eligibility basics
- Ages 2–17
- RecruitingPhase 2
A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis
AstraZeneca
- Location
- La Jolla, CA + 20 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis
AbbVie
- Location
- Beverly Hills, CA + 48 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
Eli Lilly and Company
- Location
- Fountain Valley, CA + 37 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Investigate the Clinical Effect and the Safety of PRX-115 Infused Intravenously at Different Dosing Regimens, With and Without Methotrexate, Versus Placebo in Adults Gout Patients (RELEASE)
Protalix
- Location
- Anaheim, CA + 25 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Dotinurad Versus Allopurinol in Participants With Gout
Crystalys Therapeutics
- Location
- Covina, CA + 81 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study of Dotinurad Versus Allopurinol in Tophaceous Gout
Crystalys Therapeutics
- Location
- Covina, CA + 82 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Phase 2 Trial of Dotinurad in Xanthine Oxidase Inhibitor (XOI) Intolerant/Uricase Failure Gout Participants
Crystalys Therapeutics
- Location
- Granada Hills, CA + 40 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Study to Evaluate the Efficacy and Safety of JNJ-88545223 for the Treatment of Participants With Active Psoriatic Arthritis
Janssen Research & Development, LLC
- Location
- Huntington Beach, CA + 17 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
Eli Lilly and Company
- Location
- Palm Springs, CA + 34 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)
UCB Biopharma SRL
- Location
- Santa Monica, CA + 5 other US sites
- Eligibility basics
- Ages 18+ · Women only
- RecruitingPhase 1
Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants
AstraZeneca
- Location
- Fullerton, CA + 2 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
Continuation Study of Zasocitinib in Adults With Psoriatic Arthritis
Takeda
- Location
- Fountain Valley, CA + 18 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Osteoarthritis Pain
Eli Lilly and Company
- Location
- Palm Springs, CA + 35 other US sites
- Eligibility basics
- Ages 40+
- RecruitingPhase 1/Phase 2
FT839 in Autoimmune Diseases
Fate Therapeutics
- Location
- Fullerton, CA
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1/Phase 2
Evaluation of Intra-articular CX-011 to Treat Moderate to Severe Pain From Knee Osteoarthritis
CarthroniX, Inc.
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 40–75
Who these studies look for
Most require a confirmed diagnosis, often with X-rays or blood tests, and set rules for pain medicines during the study.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Can I keep taking my pain medicine?
Some studies allow it, some require a washout period first. The study team will explain the rules before you agree to anything.