Diabetes · California
Diabetes studies in California
100 studies have at least one recruiting site in California. Diabetes research covers type 1 and type 2 diabetes, prediabetes and related complications, testing medicines, devices such as glucose monitors and insulin pumps, and lifestyle programs.
100 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
5 studies with pay posted
Exact amounts posted by the research company for each study. The button opens that study’s own page.
Pays up to
$32,450
Clinical Trial for People with Type 2 Diabetes (S-38170)
Altasciences · Cypress, CA
Two schedule options (up to $18,050 or up to $32,450), with multi-night stays and outpatient visits.
Ages 18+ · Male/Female
View study & apply (opens in a new tab)Opens Altasciences’s page for this exact study
Pays up to
$30,000
Clinical Trial for People Living with Type 2 Diabetes (S-36900)
Altasciences · Cypress, CA
Ages 18+ · Male/Female
View study & apply (opens in a new tab)Opens Altasciences’s page for this exact study
Pays up to
$26,700
Diabetes Type 2
CenExel · Anaheim, CA
Ages 18–70 · Male/Female
View study & apply (opens in a new tab)Opens CenExel’s page for this exact study
Pays up to
$25,725
Clinical Study for People with Type 2 Diabetes (S-40910)
Altasciences · Cypress, CA
Ages 18–64 · Male/Female
View study & apply (opens in a new tab)Opens Altasciences’s page for this exact study
Pays up to
$3,220
Diabetes Study
CenExel · Los Alamitos, CA
Ages 18+ · Male/Female
View study & apply (opens in a new tab)Opens CenExel’s page for this exact study
More recruiting studies (pay not posted)
- RecruitingHealthy volunteersPhase 1Overnight stay mentioned
A Study to Investigate the Relative Bioavailability and Safety of Different Oral Formulations of Elecoglipron in Healthy Participants
AstraZeneca
- Location
- Glendale, CA + 1 other US site
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Orally Administered TIX100 in Healthy Subjects
TIXiMED, Inc.
- Location
- Chula Vista, CA
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 1
Safety and Drug Concentrations of REGN20934 in Adults With Overweight or Obesity
Regeneron Pharmaceuticals
- Location
- Glendale, CA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4248 in Healthy Participants and Participants With Chronic Kidney Disease and Type 2 Diabetes and to Assess Home Measurements of…
AstraZeneca
- Location
- Glendale, CA + 3 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1
A Trial Evaluating AMG 127 in Healthy Participants and Participants With Type 2 Diabetes Mellitus
Amgen
- Location
- Lake Forest, CA + 1 other US site
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study of MET233 in Combination With MET097 in Individuals With Obesity or Overweight With or Without Diabetes
Pfizer
- Location
- Cypress, CA
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1/Phase 2
Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions
Thomas Advanced Medical LLC
- Location
- Culver City, CA
- Eligibility basics
- Ages 18+
- RecruitingPhase 1Overnight stay mentioned
A Study of GNTI-122 in Adults Recently Diagnosed With T1D
GentiBio, Inc
- Location
- Duarte, CA + 8 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersEarly Phase 1
Precision Dosing of Metformin in Youth With T2D
University of California, San Francisco
- Location
- Oakland, CA + 1 other US site
- Eligibility basics
- Ages 10–21
- RecruitingHealthy volunteersPhase 3
A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
- Location
- Fountain Valley, CA + 55 other US sites
- Eligibility basics
- Ages 18–79
- RecruitingHealthy volunteers
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
Cleerly, Inc.
- Location
- Beverly Hills, CA + 121 other US sites
- Eligibility basics
- Ages 55+
- RecruitingPhase 3
A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-004)
Merck Sharp & Dohme LLC
- Location
- Glendale, CA + 27 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus
AstraZeneca
- Location
- Encinitas, CA + 12 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
SPYRAL GEMINI Pilot Study
Medtronic Vascular
- Location
- Stanford, CA + 11 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
A Study to Evaluate ALN-4324 on Insulin Sensitivity in Adults With Type 2 Diabetes Mellitus
Alnylam Pharmaceuticals
- Location
- Chula Vista, CA
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Mellitus Who Are Not Achieving Glycemic Targets While Using GLP-1-Based Therapy
Biomea Fusion Inc.
- Location
- Canoga Park, CA + 19 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
Evaluation of MiniMed Next Generation Extended Wear Sensors and Algorithm in Patients With Type 1 and Type 2 Diabetes
Medtronic MiniMed, Inc.
- Location
- Chula Vista, CA + 9 other US sites
- Eligibility basics
- Ages 2–80
- RecruitingPhase 2
Study to Evaluate HM15275 in Subjects With Type 2 Diabetes Mellitus
Hanmi Pharmaceutical Company Limited
- Location
- Santa Clarita, CA + 19 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Study to Test Whether BI 1815368 Helps People With an Eye Condition Called Diabetic Macular Edema
Boehringer Ingelheim
- Location
- Arcadia, CA + 21 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
Surabgene Lomparvovec Administered in the Suprachoroidal Space in Adult Participants With Diabetic Retinopathy Without Center-Involved Diabetic Macular Edema
AbbVie
- Location
- Bakersfield, CA + 36 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Research Study Investigating How Adults With Overweight or Obesity, With or Without Type 2 Diabetes, Tolerate Switching to a New Treatment (Zenagamtide) From Their Current Semaglutide Medication
Novo Nordisk A/S
- Location
- Glendale, CA + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Research Study Investigating How Adults With Overweight or Obesity, With or Without Type 2 Diabetes, Tolerate Switching to a New Treatment (Zenagamtide) From Their Current Tirzepatide Medication
Novo Nordisk A/S
- Location
- Glendale, CA + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy
Vertex Pharmaceuticals Incorporated
- Location
- Fresno, CA + 57 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Boehringer Ingelheim
- Location
- Beverly Hills, CA + 199 other US sites
- Eligibility basics
- Ages 18+
Who these studies look for
Studies commonly set an HbA1c range, a diagnosis duration and a list of allowed or excluded medications. Some also recruit people without diabetes as a comparison group.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Will I have to stop my diabetes medicine?
Some studies change or pause medicines under close supervision; many add a study treatment on top of your current care. Never change medicines on your own; the study team and your doctor decide this together.