Sleep · California
Sleep studies in California
46 studies have at least one recruiting site in California. Sleep research includes insomnia, sleep apnea, narcolepsy and circadian rhythm studies. Some involve nights in a sleep lab; others use wearables or questionnaires at home.
46 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
1 study with pay posted
Exact amounts posted by the research company for each study. The button opens that study’s own page.
Pays up to
$10,000
Research Study for Insomnia (S-41000)
Altasciences · Cypress, CA
Ages 18+ · Male/Female
View study & apply (opens in a new tab)Opens Altasciences’s page for this exact study
More recruiting studies (pay not posted)
- RecruitingHealthy volunteersPhase 1
TREAD: Time Restricted Eating Intervention for Alzheimer's Disease
University of California, San Diego
- Location
- San Diego, CA
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteers
GUT-FEELINGS: Using Citizen Science for Large-Scale Prebiotic Clinical Trials for Mental Wellness in Adults
Holobiome, Inc.
- Location
- Del Mar, CA
- Eligibility basics
- Ages 21–80
- RecruitingHealthy volunteers
The Effects of a Nutritional Supplement on Sleep Quality
Athletic Greens International
- Location
- Santa Monica, CA
- Eligibility basics
- Ages 35–65
- RecruitingPhase 3
Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol
Axsome Therapeutics, Inc.
- Location
- Bellflower, CA + 35 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
DReAMzz- Dronabinol and Acetazolamide Medication for Sleep Apnea (ZZ). Dose Confirmation Crossover Study for IHL-42X in Subjects With Obstructive Sleep Apnea.
Incannex Healthcare Ltd
- Location
- Chula Vista, CA + 11 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
A Study to Learn About the Monthly Dosing Study Medicine Called Berobenatide in Adults With Breathing Problems During Sleep and Overweight or Obesity Who Use a Breathing Machine (PAP) (VESPER-OSA 1)
Pfizer
- Location
- Riverside, CA + 2 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
A Long-Term Study of ALKS 2680 in Subjects With Narcolepsy and Idiopathic Hypersomnia
Alkermes, Inc.
- Location
- Los Angeles, CA + 32 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 2
A Study of TAK-360 in Adults With Narcolepsy Without Cataplexy (NT2)
Takeda
- Location
- Chula Vista, CA + 24 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight
Eli Lilly and Company
- Location
- Long Beach, CA + 22 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study Evaluating the Efficacy and Safety of Xywav Expanded Dosing vs Placebo in Participants With Narcolepsy or IH
Jazz Pharmaceuticals
- Location
- Irvine, CA + 14 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolepsy Type 1
Alkermes, Inc.
- Location
- Los Angeles, CA + 21 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolepsy Type 2
Alkermes, Inc.
- Location
- Los Angeles, CA + 21 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms
Janssen Research & Development, LLC
- Location
- Anaheim, CA + 41 other US sites
- Eligibility basics
- Ages 18–74
- RecruitingPhase 3
A Study of Suvorexant (MK-4305) for the Treatment of Insomnia Disorder in Participants With Opioid Use Disorder (MK-4305-098)
Merck Sharp & Dohme LLC
- Location
- Garden Grove, CA + 12 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 2/Phase 3
A Study of TAK-360 in People With Narcolepsy or Idiopathic Hypersomnia
Takeda
- Location
- Chula Vista, CA + 16 other US sites
- Eligibility basics
- Ages 18–71
- RecruitingPhase 3
A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Idiopathic Hypersomnia (IH)
Harmony Biosciences Management, Inc.
- Location
- Redwood City, CA + 39 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea
Novo Nordisk A/S
- Location
- San Diego, CA + 14 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Narcolepsy
Harmony Biosciences Management, Inc.
- Location
- Los Angeles, CA + 26 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Pitolisant in Patients With Prader-Willi Syndrome
Harmony Biosciences Management, Inc.
- Location
- Los Angeles, CA + 18 other US sites
- Eligibility basics
- Ages 6+
- RecruitingPhase 3
Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work Disorder (SUSTAIN)
Axsome Therapeutics, Inc.
- Location
- Anaheim, CA + 37 other US sites
- Eligibility basics
- Ages 18–65
- Recruiting
Effectiveness of Audio Cues to Achieve Positional Therapy in Patients With Positional Obstructive Sleep Apnea
SleepDev, Inc
- Location
- Burlingame, CA
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
ISP-001: Sleeping Beauty Transposon-Engineered B Cells for MPS I
Immusoft of CA, Inc.
- Location
- Oakland, CA + 1 other US site
- Eligibility basics
- Ages 10+
- RecruitingPhase 2
A Study of TAK-360 in Adults With Idiopathic Hypersomnia
Takeda
- Location
- Redwood City, CA + 12 other US sites
- Eligibility basics
- Ages 18–70
- Recruiting
Optimizing Extended-Duration (XD-) TOMAC Therapy for Restless Legs Syndrome (RLS)
Noctrix Health, Inc.
- Location
- Pleasanton, CA
- Eligibility basics
- Ages 21+
Who these studies look for
Sleep studies often ask about shift work, caffeine and alcohol use, and medicines that affect sleep. Overnight lab studies usually require you to keep a set sleep schedule beforehand.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do sleep studies require staying overnight?
Not always. Some use a sleep lab, some use home monitoring. Where a record mentions an overnight or inpatient stay we flag it, but the site confirms the schedule.