Smoking & vaping · California
Smoking and vaping studies in California
19 studies have at least one recruiting site in California. Tobacco research includes quit-smoking and quit-vaping programs, new cessation medicines and studies of how nicotine products affect the body.
19 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1
Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 21–65
- RecruitingHealthy volunteersPhase 1
Age-dependent Effects of Smoked and Oral Delta-9-THC
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
Studying NMDA and Sigma-1 in Smoking Cessation Treatment (SUMMIT)
Axsome Therapeutics, Inc.
- Location
- Lemon Grove, CA + 24 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteers
MATAspire: Mental Health Awareness Tailored App for Substance Prevention and Integrated Resilience Education
California State University, Northridge
- Location
- Northridge, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Using Nicotine to Reverse Age-related Auditory Processing Deficits
University of California, Irvine
- Location
- Irvine, CA + 1 other US site
- Eligibility basics
- Ages 18–85
- RecruitingHealthy volunteersPhase 2
Ongoing Lung Decline With Age Intensified Response
Cedars-Sinai Medical Center
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteers
Smoking Cessation CM for Veterans With or at Risk for Cancer
VA Office of Research and Development
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Trauma-Informed Care for Smoking Cessation for Pregnancy
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18+ · Women only
- RecruitingHealthy volunteers
Evaluating the Impact of CONNECT in a Multilingual Population
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 50–80
- RecruitingHealthy volunteers
Social Media Influences on Engagement and Susceptibility to Non-combustible Tobacco Product Use Among Youth and Young Adults (AYA)
University of Southern California
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 14–17
- RecruitingHealthy volunteers
Social Media Support Groups for Adolescent Vaping Cessation
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 13+
- RecruitingHealthy volunteers
Brain/Craving Response to Smoking Cues After Oral Nicotine Pouch Use
University of Southern California
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 21–55
- RecruitingHealthy volunteers
Abuse Liability and Appeal of Oral Nicotine Products
University of Southern California
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 21–25
- RecruitingHealthy volunteers
Melanin and Dermal Uptake of Thirdhand Cigarette Smoke
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18–50
- RecruitingHealthy volunteers
Measuring Environmental Tobacco and Cannabis: Pollutants and Exposures
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 21–50
- RecruitingHealthy volunteers
Lung Macrophage Populations and Functions in Chronic Obstructive Pulmonary Disease (COPD)-Susceptible Smokers
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 40–75
- RecruitingHealthy volunteers
Healthy Family Project: Tobacco Use and Smoke Exposure in Asian American Communities
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 2
Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 21–65
- RecruitingHealthy volunteers
Smoke-free Home Study in Subsidized Housing
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18+
Who these studies look for
Most require current smoking or vaping at a set level, measured at screening. Quit studies often include counseling.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do I have to quit to join?
Cessation studies are for people who want to quit. Other tobacco studies may ask you to keep your usual habits or switch products for a period. The listing explains which.