Skip to content
Bored Studies
RecruitingAccepts healthy volunteers

Melanin and Dermal Uptake of Thirdhand Cigarette Smoke

University of California, San Francisco · NCT06020248

View Study & Apply (opens in a new tab)

Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–50 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
60
US sites recruiting
1
Study start
September 1, 2023
Record last updated
June 16, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This is a pilot study of the effects of dermal melanin on dermal uptake and retention of nicotine. The initial hypothesis is that higher levels of dermal melanin will correlate with lower uptake and longer retention of nicotine in the skin and body.

Being studied: Wear clothing that has been exposed to cigarette smoke for 3 hours.

Conditions: Healthy

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Adult nonsmoker
  • Aged 18-50
  • Skin reflectance scores below 150 or above 249 using the Mexameter 18 instrument
  • Healthy on the basis of medical history
  • Systolic blood pressure \<150
  • Diastolic blood pressure \<100
  • C-reactive protein \<3.1 mg/ml
  • Liver function (AST and ALT) in normal ranges
  • kidney function (BUN) in normal ranges
  • LDL\<131
  • Blood glucose \<110
  • Not exposed to tobacco SHS.

Exclusion Criteria

  • Dermal skin reflectance score between 150 and 249, as measured by the Mexameter 18 instrument.
  • Positive SARS-CoV-2 antibody test
  • Age 18 \< or > 50
  • Physician diagnosis of asthma, heart disease, hypertension, thyroid disease, diabetes, renal or liver impairment or glaucoma.
  • Unstable psychiatric condition (such as current major depression, history of schizophrenia or bipolar disorder) or current use of more than two psychiatric medications
  • Systolic blood pressure greater than or equal to 150
  • Diastolic blood pressure greater than or equal to 100
  • Blood glucose greater than or equal to 110
  • LDL greater than or equal to130
  • Pregnancy or breastfeeding (by urine hCG and/or history)
  • Alcohol or illicit drug dependence within the past 5 years
  • BMI > 35 and \< 18
  • Current illicit drug use (by history or urine test)
  • More than 1 pack year smoking history
  • Ever a daily marijuana smoker
  • Smoked anything within the last 3 months
  • Unable to hold allergy or other OTC medicines
  • Occupational exposure to smoke, dusts OR fumes
  • Concurrent participation in another clinical trial
  • Unable to communicate in English
  • No social security number

Recruiting US locations

  • Zuckerberg San Francisco General Hospital

    San Francisco, CA 94110

    Site contact: Abel Huang · Abel.Huang@ucsf.edu

Study contacts (from the official record)

  • Suzaynn F Schick, PhD · 415-514-3535 · suzaynn@gmail.com
  • Abel Huang, BS · (415) 514-9011 · abel.huang@ucsf.edu
All smoking & vaping studies in California →
Melanin and Dermal Uptake of Thirdhand Cigarette Smoke (NCT06020248) | Bored Studies