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RecruitingAccepts healthy volunteersPhase 4

Bupivacaine With Epinephrine Over Diaphragm in Laparoscopy

Cedars-Sinai Medical Center · NCT07400146

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · Women only
Healthy volunteers
Accepted
Study type
Interventional · Phase 4
Target enrollment
100
US sites recruiting
1
Study start
March 2, 2026
Record last updated
September 30, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Postoperative shoulder pain is often reported to be particularly bothersome after laparoscopy. The benefits of local anesthetic, such as bupivacaine, applied to subcutaneous tissue for general postoperative pain management after surgery is well established. However, there have been no studies on sprayed bupivacaine over the diaphragm to reduce shoulder pain in laparoscopic surgery. The purpose of the study is to evaluate if sprayed infra-diaphragmatic bupivacaine compared to placebo (saline) will improve postoperative shoulder pain in patients undergoing benign laparoscopic gynecologic surgery. The entire study will be conducted at Cedar Sinai Medical Center.

Being studied: Instillation of Bupivacaine with epinephrine over the diaphragm

Conditions: Postoperative Pain; Shoulder Pain

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Provide a signed and dated informed consent form
  • Stated willingness to comply with all study procedures and availability for the duration of the study
  • 8 years of age or older
  • Undergoing laparoscopic surgery at Cedars-Sinai Medical Center with a surgeon in the Minimally Invasive Gynecologic Surgery division.

Exclusion Criteria

  • Pregnancy
  • Urgent/non-scheduled surgery
  • Scheduled for planned or possible concomitant non-gynecologic surgery (e.g., urologic or colorectal procedure)
  • Baseline shoulder pain
  • Baseline opioid use
  • Baseline of chronic pain syndrome
  • Conversion to open surgery
  • Allergy or intolerance to bupivacaine, lidocaine (or amide class of anesthetics), oxycodone, acetaminophen, or ibuprofen
  • Planned post-operative admission

Recruiting US locations

  • Cedars Sinai Medical Center

    Los Angeles, CA 90048

    Site contact: Ogechukwu Ezike, MD · 3473371181 · ogechukwu.ezike@cshs.org

Study contacts (from the official record)

  • Ogechukwu Ezike, MD · 3473371181 · ogechukwu.ezike@cshs.org
  • Kelly Wright, MD · kelly.wright@cshs.org
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Bupivacaine With Epinephrine Over Diaphragm in Laparoscopy (NCT07400146) | Bored Studies