Study type
Pain studies recruiting now
Pain research covers chronic back pain, fibromyalgia, nerve pain and short-term pain after procedures, testing medicines, devices and non-drug approaches.
115 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
4 studies with pay posted
Exact amounts posted by the research company for each study. The button opens that study’s own page.
Pays up to
$3,400
Osteoarthritis of the Knee
CenExel · Salt Lake City, UT
Ages 18–75 · Male/Female
View study & apply (opens in a new tab)Opens CenExel’s page for this exact study
Pays up to
$2,000
Hernia Repair – Inguinal (Groin Area)
CenExel · Anaheim, CA
Ages 18+ · Male/Female
View study & apply (opens in a new tab)Opens CenExel’s page for this exact study
Pays up to
$1,800
Bunion Removal Study
CenExel · Salt Lake City, UT
Ages 18–65 · Male/Female
View study & apply (opens in a new tab)Opens CenExel’s page for this exact study
Pays up to
$1,000
Wisdom Teeth Removal Study
CenExel · Salt Lake City, UT
Ages 18–45 · Male/Female
View study & apply (opens in a new tab)Opens CenExel’s page for this exact study
More recruiting studies (pay not posted)
- RecruitingHealthy volunteersPhase 1Overnight stay mentioned
Phase 1 Study of SBS-147 in Healthy Adults
Sparian Biosciences, Inc
- Location
- Cypress, CA
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
Safety, Tolerability, and Pharmacokinetics of ASCT-83 in Healthy Adults
Alcamena Stem Cell Therapeutics
- Location
- Saint Paul, MN
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteersPhase 1
Sustained Acoustic Medicine for Osteoarthritis Pain
ZetrOZ, Inc.
- Location
- Tampa, FL
- Eligibility basics
- Ages 35–85
- RecruitingPhase 1Overnight stay mentioned
MAD Study to Assess the Safety, Tolerability, PKs and Efficacy of YJ001 for Spray Use in Patients With DPNP
Zhejiang Hanmai Pharmaceutical Technology Co., Ltd.
- Location
- Fredericksburg, TX
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersOvernight stay mentioned
The Osteoarthritis Prevention Study
Wake Forest University
- Location
- Boston, MA + 1 other US site
- Eligibility basics
- Ages 50+ · Women only
- RecruitingHealthy volunteersPhase 1/Phase 2
Vasopressin and Pain Perception in the Brain
University of Maryland, Baltimore
- Location
- Baltimore, MD
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersEarly Phase 1
JIT: Effect of Pain on DT in TMD
University of Minnesota
- Location
- Minneapolis, MN
- Eligibility basics
- Ages 21–65
- RecruitingHealthy volunteersEarly Phase 1
Zynrelef vs Exparel: The Battle of Postoperative Pain Control After Robotic Sleeve Gastrectomy
Texas Tech University Health Sciences Center
- Location
- Lubbock, TX
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersEarly Phase 1
Brain Mechanisms Supporting Cannabis-induced Pain Relief
University of California, San Diego
- Location
- La Jolla, CA
- Eligibility basics
- Ages 21–65
- RecruitingHealthy volunteersPhase 1
Assessment of Neuroinflammation in Central Inflammatory Disorders Using [F-18]DPA-714.
University of Alabama at Birmingham
- Location
- Birmingham, AL
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
Hormones, Outcomes, and Pain Pathways in Exercise Study
University of Houston
- Location
- Houston, TX
- Eligibility basics
- Ages 18–60 · Women only
- RecruitingHealthy volunteersPhase 1/Phase 2
ACTION: Trial of Adding Buprenorphine, CBT, and TMS to Improve Outcomes of Long-Term Opioid Therapy for Chronic Pain
Medical University of South Carolina
- Location
- Charleston, SC
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches
State University of New York - Upstate Medical University
- Location
- Syracuse, NY
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 4Overnight stay mentioned
Simethicone as Part of ERAS in Bariatric Surgery Patients
Madigan Army Medical Center
- Location
- Tacoma, WA
- Eligibility basics
- Ages 18–89
- RecruitingPhase 3
An Open-Label, Safety and Efficacy Study of Cebranopadol in Participants With Acute Pain With Surgical or Non-Surgical Origin
Adneuris Therapeutics, Inc.
- Location
- Phoenix, AZ + 14 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Study of Cebranopadol for Opioid Withdrawal Symptoms in Adults With Chronic Pain
Adneuris Therapeutics, Inc.
- Location
- North Canton, OH + 1 other US site
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
Efficacy and Safety of VER-01 in the Treatment of Participants With Chronic Painful Lumbosacral Radiculopathy
Vertanical GmbH
- Location
- Mobile, AL + 22 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Study to Evaluate Safety of C-1101 Versus Sterile Saline in Adults With Chronic Painful Lumbosacral Radiculopathy
Consano Bio
- Location
- Fernandina Beach, FL + 1 other US site
- Eligibility basics
- Ages 18–70
- Recruiting
MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion
Kuros Biosurgery AG
- Location
- Hartford, CT + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy
Vertex Pharmaceuticals Incorporated
- Location
- Anniston, AL + 57 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease
DiscGenics, Inc.
- Location
- Birmingham, AL + 29 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control
Boston Scientific Corporation
- Location
- Greenwood, CO + 6 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
Eli Lilly and Company
- Location
- Mobile, AL + 37 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
Eli Lilly and Company
- Location
- Birmingham, AL + 34 other US sites
- Eligibility basics
- Ages 18+
Who these studies look for
Studies usually set a pain score range and limits on pain medicines. Some short-term pain studies involve a scheduled minor procedure.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
What is an acute pain study?
Some studies measure pain relief after a planned minor procedure, such as dental surgery or bunion removal, performed as part of the study. Each listing describes what is involved.