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Hormones, Outcomes, and Pain Pathways in Exercise Study

University of Houston · with National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), The University of Texas Health Science Center, Houston · NCT07579182

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–60 · Women only
Healthy volunteers
Accepted
Study type
Interventional · Phase 1
Target enrollment
140
US sites recruiting
1
Study start
May 17, 2026
Record last updated
June 2, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of the proposed project is to evaluate a mechanical intervention (sports bras designed specifically for full busted women) to alleviate neck, shoulder, arm, and back pain in full-busted women and investigate the contribution of non-mechanical pathways associated with this type of pain in women. Specifically, the investigators will investigate how sex-hormones, inflammation, and remapping of specific regions of the brain contribute to the manifestation of neck, shoulder, arm, and back pain in full-busted women across the lifespan.

Being studied: Interventional Sports bra

Conditions: Breast Pain; Mastalgia; Back Pain; Back Pain, Low; Neck Pain; Chest Pain; Activity, Motor; Healthy Aging; Weight, Body; Inflammation; Gonadal Steroid Hormones; Neuronal Plasticity; Neuromuscular Manifestations

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Able to provide informed consent
  • Age of 18 to 60 years
  • Assigned female sex at birth
  • Right-handed by self-declaration
  • Willing to participate in one online testing session and up to four in-person testing sessions
  • Bra band size between 32-40"
  • International Physical Activity Questionnaire - Short Form (IPAQ-SF) score of 2 or higher
  • An answer of "NO" to any item of the general health questions of the PARQ+
  • No history of surgery to the: back, neck, or shoulders or joint replacement
  • No history of implanted pacemakers or other stimulation devices
  • No history of spinal cord injury (SCI)

Exclusion Criteria

  • Inability to provide informed consent
  • Age 17 years old or younger or 61 years or older
  • Assigned male sex at birth
  • Left-handed by self-declaration
  • Not willing to participate in one online testing session and up to four in-person testing sessions
  • Bra band size greater than 40" or less than 32"
  • IPAQ-SF score of 1 or lower
  • An answer of "YES" to any item of the general health questions of the PARQ+
  • History of limb amputation (upper or lower extremity)
  • Presence of open pressure sores on the upper or lower extremities
  • Currently pregnant or lactating/breastfeeding
  • History of surgery to the: back, neck, or shoulders or joint replacement
  • History of breast cancer and/or mastectomy
  • History of implanted pacemakers or other stimulation devices
  • History of spinal cord injury (SCI)
  • History of joint disease including osteoarthritis and/or Rheumatoid Arthritis
  • History of the following neurological diseases: Cerebrovascular accident (CVA, stroke), Alzheimer's Disease (AD), Dementia (of any form), Huntington's Disease, Traumatic Brain Injury (TBI), Spinal cord injury (SCI), Multiple Sclerosis (MS), Parkinson's Disease (PD), Polio, Paraproteinaemic Demyelinating Neuropathy (PDN) and/or Monoclonal Gammopathy of Undetermined Significance (MGUS), Myasthenia Gravis, Muscular Dystrophy, Guillain-Barré Syndrome, Scoliosis, Charcot-Marie-Tooth Disorder or other hereditary neuropathies

Additional Inclusion Criteria for Intervention Group:

a. Self-declared breast size of D-I cup (US sizes: D, E, F, G, H)

Additional Inclusion Criteria for the Control Group:

a. Self-declared breast size of A-C cup (US sizes: AA, A, B, C)

Recruiting US locations

  • University of Houston

    Houston, TX 77204

    Site contact: Stacey L Gorniak, PhD · 713-743-4802 · sgorniak@uh.edu

Study contacts (from the official record)

  • Stacey L Gorniak, PhD · 713-743-4802 · sgorniak@uh.edu
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Hormones, Outcomes, and Pain Pathways in Exercise Study (NCT07579182) | Bored Studies