Weight loss · Texas
Weight loss and obesity studies in Texas
77 studies have at least one recruiting site in Texas. Weight-management research includes trials of new medicines, devices, diets and lifestyle programs for people with overweight or obesity, and studies of weight-related conditions such as fatty liver disease.
77 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
2 studies with pay posted
Exact amounts posted by the research company for each study. The button opens that study’s own page.
Pays up to
$43,000
Clinical Research Study of an Investigational Medication in Healthy Volunteers living with Overweight or Obesity
ICON · San Antonio, TX
Participation in this study includes 1 screening visit, 1 stay of 1 night, 4 stays of 2 nights, 1 stay of 4 nights, 12 follow-up outpatient visits, and 13 phone calls.
Ages 18–64 · Male/Female · Smoker / Non Smoker
View study & apply (opens in a new tab)Opens ICON’s page for this exact study
Pays up to
$23,000
Clinical Research Study of an Investigational Medication in Healthy Volunteers living with Overweight or Obesity
ICON · San Antonio, TX
Participation in this study includes 1 screening visit, 1 stay of 6 nights, 3 stays of 5 nights, and 5 outpatient visits.
Ages 18–55 · Male/Female · Smoker / Non Smoker
View study & apply (opens in a new tab)Opens ICON’s page for this exact study
More recruiting studies (pay not posted)
- RecruitingHealthy volunteersPhase 1Overnight stay mentioned
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight
Eli Lilly and Company
- Location
- San Antonio, TX
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Study of LY4174794 in Participants With Obesity or Overweight Who Are Otherwise Healthy
Eli Lilly and Company
- Location
- San Antonio, TX
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Study of Eloralintide (LY3841136) in Female Participants With Obesity or Overweight
Eli Lilly and Company
- Location
- Dallas, TX + 1 other US site
- Eligibility basics
- Ages 18–60 · Women only
- RecruitingHealthy volunteersPhase 1
A Study of LY4329090 in Participants With Obesity or Overweight Who Are Otherwise Healthy
Eli Lilly and Company
- Location
- Dallas, TX + 1 other US site
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
Study of GS-4571 in Healthy Participants, Nondiabetic Obese Participants, and Nonobese Participants With Type 2 Diabetes Mellitus (T2DM)
Gilead Sciences
- Location
- San Antonio, TX + 2 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Study to Evaluate the Impact of Renal Impairment on the Pharmacokinetics (PK) of Ribupatide
Kailera
- Location
- San Antonio, TX + 1 other US site
- Eligibility basics
- Ages 18–85
- RecruitingHealthy volunteersPhase 1/Phase 2
First-in-human Study of the Safety, Tolerability, Pharmacokinetics, and Food Effect of ACCG-2671
Aconcagua Bio, Inc. a wholly owned subsidiary of Structure Therapeutics
- Location
- Webster, TX + 2 other US sites
- Eligibility basics
- Ages 25–75
- RecruitingHealthy volunteersEarly Phase 1
Sympathetic Transduction in Obesity-associated Hypertension (OB-HTN)
University of Texas Southwestern Medical Center
- Location
- Dallas, TX
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
Hormones, Outcomes, and Pain Pathways in Exercise Study
University of Houston
- Location
- Houston, TX
- Eligibility basics
- Ages 18–60 · Women only
- RecruitingHealthy volunteersPhase 3
A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
- Location
- Austin, TX + 55 other US sites
- Eligibility basics
- Ages 18–79
- RecruitingPhase 3
Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)
Amgen
- Location
- Austin, TX + 51 other US sites
- Eligibility basics
- Ages 18–99
- RecruitingPhase 1
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Two Formulations of ASC36 Injection in Participants With Obesity or Overweight
Ascletis Pharma (China) Co., Limited
- Location
- San Antonio, TX + 1 other US site
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities
AbbVie
- Location
- Amarillo, TX + 58 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes
Novo Nordisk A/S
- Location
- Houston, TX + 13 other US sites
- Eligibility basics
- Ages 10–18
- RecruitingPhase 1
Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events
Novo Nordisk A/S
- Location
- Amarillo, TX + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study to Assess the Effect and Safety of ALV-100 on Maintenance of Weight Loss
Alveus Therapeutics, Inc.
- Location
- Irving, TX + 19 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
The RESET System Pivotal Clinical Trial (Protocol Revision K)
Morphic Medical Inc.
- Location
- Atascocita, TX + 25 other US sites
- Eligibility basics
- Ages 22–65
- Recruiting
Randomized Study on Transoral Outlet Reduction and Lifestyle Changes for Weight Regain After Gastric Bypass
Boston Scientific Corporation
- Location
- Houston, TX + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
Hoffmann-La Roche
- Location
- Bellaire, TX + 43 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
Hoffmann-La Roche
- Location
- Brownsville, TX + 44 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
Pfizer
- Location
- Houston, TX + 29 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
AstraZeneca
- Location
- Dallas, TX + 43 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
Eli Lilly and Company
- Location
- Houston, TX + 24 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight
Eli Lilly and Company
- Location
- Houston, TX + 17 other US sites
- Eligibility basics
- Ages 18+ · Women only
Who these studies look for
Most of these studies set a BMI range and may exclude people taking certain weight-loss medicines or who have had bariatric surgery. Some require a weight-related condition such as type 2 diabetes or high blood pressure.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Can I join a weight loss study if I already take a GLP-1 medicine?
It depends on the study. Many exclude people currently or recently on weight-loss medicines; others are designed specifically for them. The listing’s eligibility criteria and the study team are the only reliable answer.