Study type
Weight loss and obesity studies recruiting now
Weight-management research includes trials of new medicines, devices, diets and lifestyle programs for people with overweight or obesity, and studies of weight-related conditions such as fatty liver disease.
365 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
11 studies with pay posted
Exact amounts posted by the research company for each study. The button opens that study’s own page.
Pays up to
$43,000
Clinical Research Study of an Investigational Medication in Healthy Volunteers living with Overweight or Obesity
ICON · San Antonio, TX
Participation in this study includes 1 screening visit, 1 stay of 1 night, 4 stays of 2 nights, 1 stay of 4 nights, 12 follow-up outpatient visits, and 13 phone calls.
Ages 18–64 · Male/Female · Smoker / Non Smoker
View study & apply (opens in a new tab)Opens ICON’s page for this exact study
Pays up to
$32,150
Clinical Trial for Healthy Adults with Overweight or Obesity (N-38160)
Altasciences · Cypress, CA
Two schedule options (up to $17,750 or up to $32,150), with multi-night stays and outpatient visits.
Ages 18+ · Male/Female
View study & apply (opens in a new tab)Opens Altasciences’s page for this exact study
Pays up to
$25,000
Research Study for Obesity (N-34300)
Altasciences · Cypress, CA
Ages 18+ · Male/Female
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Pays up to
$23,000
Clinical Research Study of an Investigational Medication in Healthy Volunteers living with Overweight or Obesity
ICON · San Antonio, TX
Participation in this study includes 1 screening visit, 1 stay of 6 nights, 3 stays of 5 nights, and 5 outpatient visits.
Ages 18–55 · Male/Female · Smoker / Non Smoker
View study & apply (opens in a new tab)Opens ICON’s page for this exact study
Pays up to
$16,050
Healthy but Overweight Volunteers Needed (N-39610)
Altasciences · Cypress, CA
Ages 18–55 · Male/Female
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Pays up to
$12,000
Clinical Research Study of an Investigational Medication in Participants with Obesity or Overweight but Otherwise Healthy
ICON · Salt Lake City, UT
Volunteers must be available for 1 stay of 6 nights (7 days) and 6 follow-up visits.
Ages 18–65 · Male/Female · Smoker / Non Smoker
View study & apply (opens in a new tab)Opens ICON’s page for this exact study
Pays up to
$11,600
Overweight Healthy Adults, Ages 18–65
Medpace · Cincinnati, OH
13 outpatient visits (including screening) plus one 5-night stay and one 4-night stay at the Phase 1 unit.
Ages 18–65 · Male/Female
View study & apply (opens in a new tab)Opens Medpace’s page for this exact study
Pays up to
$10,500
Clinical Research Study of an Investigational Medication in Overweight but Otherwise Healthy Participants
ICON · Lenexa, KS
Participation in this study includes 1 screening visit, 1 stay of 6 nights and 6 outpatient visits.
Ages 18–55 · Male/Female · Non Smoker
View study & apply (opens in a new tab)Opens ICON’s page for this exact study
Pays up to
$10,300
Study of an Investigational Drug in Adults with Overweight or Obesity (Study #250061)
QPS Missouri · Springfield, MO
Multiple return visits and daily at-home dosing.
Male/Female
View study & apply (opens in a new tab)Opens QPS Missouri’s page for this exact study
Pays up to
$7,750
Clinical Research Study of an Investigational Medication in Overweight but Otherwise Healthy Volunteers
ICON · Lenexa, KS
Participation in this study includes 1 screening visit, 1 stay of 13 nights and 1 follow-up visit.
Ages 18–55 · Male/Female · Non Smoker
View study & apply (opens in a new tab)Opens ICON’s page for this exact study
Pays up to
$6,400
Overweight / Obesity
CenExel · Anaheim, CA
Ages 18–65 · Male/Female
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More recruiting studies (pay not posted)
- RecruitingHealthy volunteersPhase 1Overnight stay mentioned
A Study to Investigate the Relative Bioavailability and Safety of Different Oral Formulations of Elecoglipron in Healthy Participants
AstraZeneca
- Location
- Glendale, CA + 1 other US site
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1Overnight stay mentioned
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight
Eli Lilly and Company
- Location
- San Antonio, TX
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1Overnight stay mentioned
A Single and Multiple Ascending Dose Study of HM17321 in Healthy and Obese Participants
Hanmi Pharmaceutical Company Limited
- Location
- Cincinnati, OH
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteers
Breastfeeding Intervention to Prevent Obesity Among Children
University of North Carolina, Greensboro
- Location
- Greensboro, NC + 1 other US site
- Eligibility basics
- Ages 0 mo+
- RecruitingHealthy volunteersPhase 1
A Study of LY4174794 in Participants With Obesity or Overweight Who Are Otherwise Healthy
Eli Lilly and Company
- Location
- San Antonio, TX
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD1043 in Healthy Adult Participants Living With Overweight and/or Obesity.
AstraZeneca
- Location
- Glendale, CA + 1 other US site
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Study of Eloralintide (LY3841136) in Female Participants With Obesity or Overweight
Eli Lilly and Company
- Location
- Daytona Beach, FL + 1 other US site
- Eligibility basics
- Ages 18–60 · Women only
- RecruitingHealthy volunteersPhase 1
A Study of LY4329090 in Participants With Obesity or Overweight Who Are Otherwise Healthy
Eli Lilly and Company
- Location
- Daytona Beach, FL + 1 other US site
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
Study of GS-4571 in Healthy Participants, Nondiabetic Obese Participants, and Nonobese Participants With Type 2 Diabetes Mellitus (T2DM)
Gilead Sciences
- Location
- Miami, FL + 2 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Orally Administered TIX100 in Healthy Subjects
TIXiMED, Inc.
- Location
- Chula Vista, CA
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 1
A Study to Evaluate the Impact of Renal Impairment on the Pharmacokinetics (PK) of Ribupatide
Kailera
- Location
- Orlando, FL + 1 other US site
- Eligibility basics
- Ages 18–85
- RecruitingHealthy volunteersPhase 1
Safety and Drug Concentrations of REGN20934 in Adults With Overweight or Obesity
Regeneron Pharmaceuticals
- Location
- Glendale, CA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASC35 Injection in Participants With Obesity or Overweight
Ascletis Pharma (China) Co., Limited
- Location
- Baltimore, MD
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1/Phase 2
First-in-human Study of the Safety, Tolerability, Pharmacokinetics, and Food Effect of ACCG-2671
Aconcagua Bio, Inc. a wholly owned subsidiary of Structure Therapeutics
- Location
- Lake Forest, CA + 2 other US sites
- Eligibility basics
- Ages 25–75
- RecruitingHealthy volunteersPhase 1
A First-in-human Research Study on How NNC0721-8060 Works in People Living With Overweight or Obesity
Novo Nordisk A/S
- Location
- Lenexa, KS
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
A Research Study on How UBT251 Affects Levels of Midazolam, Caffeine and Warfarin in the Blood of Participants With Excess Body Weight
Novo Nordisk A/S
- Location
- Cypress, CA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Study to See How Safe a New Medicine (NNC6989-0001) is in Healthy People Living With Overweight or Obesity
Novo Nordisk A/S
- Location
- Lenexa, KS
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1/Phase 2
A Phase 1/2a Study of WVE-007 in Adults Living With Overweight or Obesity
Wave Life Sciences USA, Inc.
- Location
- Baltimore, MD
- Eligibility basics
- Ages 18–60
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study of MET233 in Combination With MET097 in Individuals With Obesity or Overweight With or Without Diabetes
Pfizer
- Location
- Cypress, CA
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1
Use of Pulsatile Intravenous FSH to Mitigate Reprometabolic Syndrome
University of Colorado, Denver
- Location
- Aurora, CO
- Eligibility basics
- Ages 19–37 · Women only
- RecruitingHealthy volunteersPhase 2Overnight stay mentioned
Effects of Sucralose on Drug Absorption and Metabolism (The SweetMeds Study)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–60 · Women only
- RecruitingHealthy volunteersEarly Phase 1
Sympathetic Transduction in Obesity-associated Hypertension (OB-HTN)
University of Texas Southwestern Medical Center
- Location
- Dallas, TX
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
Alpelisib Challenge Test (ACT)
Columbia University
- Location
- New York, NY
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 1
Human Models of Selective Insulin Resistance: Alpelisib, Part I
Columbia University
- Location
- New York, NY
- Eligibility basics
- Ages 18–70
Who these studies look for
Most of these studies set a BMI range and may exclude people taking certain weight-loss medicines or who have had bariatric surgery. Some require a weight-related condition such as type 2 diabetes or high blood pressure.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Can I join a weight loss study if I already take a GLP-1 medicine?
It depends on the study. Many exclude people currently or recently on weight-loss medicines; others are designed specifically for them. The listing’s eligibility criteria and the study team are the only reliable answer.