Weight loss · Kentucky
Weight loss and obesity studies in Kentucky
24 studies have at least one recruiting site in Kentucky. Weight-management research includes trials of new medicines, devices, diets and lifestyle programs for people with overweight or obesity, and studies of weight-related conditions such as fatty liver disease.
24 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 2
Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities
AbbVie
- Location
- Louisville, KY + 58 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study to Learn About Switching to a Monthly Study Medicine Called Berobenatide (PF-08653944) to Help Keep Weight Off in People With Overweight or Obesity
Pfizer
- Location
- Louisville, KY + 4 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
Hoffmann-La Roche
- Location
- Louisville, KY + 43 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
AstraZeneca
- Location
- Louisville, KY + 43 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study of Olatorepatide in Adult Participants Living With Overweight or Obesity Without Diabetes
Regeneron Pharmaceuticals
- Location
- Lexington, KY + 20 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
Eli Lilly and Company
- Location
- Louisville, KY + 37 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight
Eli Lilly and Company
- Location
- Louisville, KY + 39 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
Eli Lilly and Company
- Location
- Louisville, KY + 42 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
Eli Lilly and Company
- Location
- Louisville, KY + 36 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
Eli Lilly and Company
- Location
- Louisville, KY + 34 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)
Amgen
- Location
- Louisville, KY + 69 other US sites
- Eligibility basics
- Ages 18–99
- RecruitingPhase 3
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
Eli Lilly and Company
- Location
- Lexington, KY + 55 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
Amgen
- Location
- Lexington, KY + 117 other US sites
- Eligibility basics
- Ages 18–99
- RecruitingPhase 3
Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body Weight
Novo Nordisk A/S
- Location
- Louisville, KY + 14 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice…
Eli Lilly and Company
- Location
- Bowling Green, KY + 38 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight
Novo Nordisk A/S
- Location
- Lexington, KY + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and…
Novo Nordisk A/S
- Location
- Lexington, KY + 55 other US sites
- Eligibility basics
- Ages 45+
- RecruitingPhase 3
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
Novo Nordisk A/S
- Location
- Lexington, KY + 129 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
Novo Nordisk A/S
- Location
- Louisville, KY + 17 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Phase 2A Clinical Trial to Assess the Safety and Tolerability of ERX1000 in Men and Women for the Treatment of Obesity.
ERX Pharmaceuticals
- Location
- Louisville, KY + 2 other US sites
- Eligibility basics
- Ages 18–60
- RecruitingPhase 1
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MBX 4291 in Adult Participants With Obesity
MBX Biosciences
- Location
- Lexington, KY + 3 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 4
The Effects of Mirabegron and Tadalafil on Glucose Tolerance in Prediabetics
Philip Kern
- Location
- Lexington, KY
- Eligibility basics
- Ages 35–65
- RecruitingHealthy volunteers
Circadian Rhythms in Postmenopausal Women
Julie Pendergast
- Location
- Lexington, KY
- Eligibility basics
- Ages 45–65 · Women only
- RecruitingHealthy volunteersPhase 2
Cannabis for Obesity Trial
Joshua A. Lile, Ph.D.
- Location
- Lexington, KY
- Eligibility basics
- Ages 18–65
Who these studies look for
Most of these studies set a BMI range and may exclude people taking certain weight-loss medicines or who have had bariatric surgery. Some require a weight-related condition such as type 2 diabetes or high blood pressure.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Can I join a weight loss study if I already take a GLP-1 medicine?
It depends on the study. Many exclude people currently or recently on weight-loss medicines; others are designed specifically for them. The listing’s eligibility criteria and the study team are the only reliable answer.