A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight
Novo Nordisk A/S · NCT07745504
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18+ · All sexes
- Healthy volunteers
- Not accepted (a condition is required)
- Study type
- Interventional · Phase 3
- Target enrollment
- 285
- US sites recruiting
- 10
- Study start
- August 4, 2026
- Record last updated
- September 4, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
The purpose of this clinical study is to look at how well a study medicine called cagrilintide helps people living with excess body weight to lose weight. Participants will either get cagrilintide, the active study medicine being tested or placebo, a medicine that has no active medicine in it. Which treatment participants get is decided by chance. Cagrilintide is a new medicine under development that doctors cannot prescribe yet, but it has been tested in humans before. Participants will be in this clinical study for about 9 months.
Being studied: Cagrilintide; Placebo cagrilintide; Placebo semaglutide
Conditions: Overweight; Obesity
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion criteria
- Informed consent obtained before any study-related activities. Study-related activities are any procedures that are carried out as part of the study, including activities to determine suitability for the study.
- Male or female (sex assigned at birth, inclusive of all gender identities).
- Age 18 years or above at the time of signing the informed consent.
- Body mass index (BMI) greater than or equal to (>=) 30.0 kilograms per square meter (kg/m\^2), or BMI >= 27.0 kg/m\^2 with the presence of at least one weight related comorbidity including, but not limited to, hypertension, dyslipidaemia, obstructive sleep apnoea or cardiovascular disease.
Exclusion criteria
- History of Type 1 Diabetes (T1D) or Type 2 Diabetes (T2D).
- Previous dosing of marketed or non-marketed amylin-based compounds.
- Treatment, or intention to initiate treatment, with any medication prescribed for the indication of weight management within 180 days before screening.
Recruiting US locations
Hope Clin Res & Wellness
Conyers, GA 30094
East West Med Res Inst
Honolulu, HI 96814
Midwest Inst For Clin Res
Indianapolis, IN 46260
The Alliance for Multispecialty Research LLC AMR
Lexington, KY 40509
PharmQuest
Greensboro, NC 27408
KDCILM, LLC & Accellacare US, Inc.
Wilmington, NC 28401
Coastal Carolina Res Ctr
North Charleston, SC 29405
Health Res of Hampton Roads
Newport News, VA 23606
National Clin Res Inc.
Richmond, VA 23294
Selma Medical Associates
Winchester, VA 22601-3834
Study contacts (from the official record)
- Novo Nordisk · (+1) 866-867-7178 · clinicaltrials@novonordisk.com
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