Location · South Carolina
Clinical trials recruiting in South Carolina
436 recruiting studies have at least one site in South Carolina; 86 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in South Carolina.
436 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- Recruiting
OurRelationship-S: A Digital Relationship-Strengthening Program for Couples Experiencing Substance Misuse
OurRelationship
- Location
- Lexington, SC + 4 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Investigating Novel Smoking Cessation Primary Care Interventions in Rural Environments
Medical University of South Carolina
- Location
- Charleston, SC
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study of BLB-201 RSV Vaccine in Infants and Children
Blue Lake Biotechnology Inc.
- Location
- Greenville, SC + 13 other US sites
- Eligibility basics
- Ages 6 mo–5
- RecruitingHealthy volunteersPhase 1/Phase 2
Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older
Sanofi
- Location
- North Charleston, SC + 49 other US sites
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteersPhase 1
First-in-Human Trial to Assess REGN20423 in Healthy Adult Participants and Adult Participants With Atopic Dermatitis
Regeneron Pharmaceuticals
- Location
- North Charleston, SC + 5 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)
Merck Sharp & Dohme LLC
- Location
- Charleston, SC + 14 other US sites
- Eligibility basics
- Ages 2 mo–1
- RecruitingHealthy volunteersPhase 1/Phase 2
Study to Assess Safety and Immunogenicity of an Egg-based H5N8 Influenza Vaccine at Multiple Dose Levels Adjuvanted With Matrix-M in Healthy Participants 18 Years of Age and Above.
Sanofi
- Location
- North Charleston, SC + 15 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersEarly Phase 1
Weekly Isotretinoin vs Tetracycline for Moderate Acne
Medical University of South Carolina
- Location
- Charleston, SC
- Eligibility basics
- Ages 12+
- RecruitingHealthy volunteersEarly Phase 1
RM1 Project 1 - tAN Naloxone
Medical University of South Carolina
- Location
- Charleston, SC
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1/Phase 2
ACTION: Trial of Adding Buprenorphine, CBT, and TMS to Improve Outcomes of Long-Term Opioid Therapy for Chronic Pain
Medical University of South Carolina
- Location
- Charleston, SC
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
Increasing Affordable Fruits and Vegetables for Families With Food Insecurity
University of South Carolina
- Location
- Columbia, SC
- Eligibility basics
- Ages 2–10
- RecruitingHealthy volunteersPhase 3
A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.
Pfizer
- Location
- Simpsonville, SC + 101 other US sites
- Eligibility basics
- Ages 1 mo–7 mo
- RecruitingHealthy volunteersPhase 3
A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
- Location
- Greer, SC + 55 other US sites
- Eligibility basics
- Ages 18–79
- RecruitingHealthy volunteersPhase 3
A Phase 3 Study of Revaccination in Subsequent Pregnancies With Bivalent RSV Vaccine and Duration of Protection of a Single Dose
Pfizer
- Location
- Greenville, SC + 76 other US sites
- Eligibility basics
- Ages 0 mo+
- RecruitingHealthy volunteersPhase 3
A Study to Assess the Safety, Tolerability, and Immunogenicity of 3 Lots of a Multivalent Pneumococcal Conjugate Vaccine Administered to Adults
Pfizer
- Location
- Moncks Corner, SC + 36 other US sites
- Eligibility basics
- Ages 18–49
- RecruitingHealthy volunteersPhase 3
A Study to Evaluate the Immune Response and Safety of a Vaccine Against Influenza in Adults 18-64 Years of Age
GlaxoSmithKline
- Location
- Spartanburg, SC + 11 other US sites
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteersPhase 3
Lot-to-lot Consistency Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From 2 Months of Age
Sanofi
- Location
- Charleston, SC + 13 other US sites
- Eligibility basics
- Ages 1 mo–2 mo
- RecruitingHealthy volunteers
Observational Study of Decentralized Urine Optical Interaction Patterns Associated With Environmental Microplastic and Nanoplastic Exposure
Ecotera Health LLC
- Location
- Charleston, SC + 50 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 3
A Study to Learn About the Safety of an Expanded Pneumococcal Vaccine in Healthy Infants
Pfizer
- Location
- Simpsonville, SC + 20 other US sites
- Eligibility basics
- Ages 1 mo–4 mo
- RecruitingHealthy volunteersPhase 3
Study to Learn About Safety, Tolerability, and Immune Response of a Catch-up Pneumococcal Vaccine in Children and Adolescents
Pfizer
- Location
- Simpsonville, SC + 49 other US sites
- Eligibility basics
- Ages 1–17
- RecruitingHealthy volunteersPhase 3
A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps, Rubella and Varicella Vaccine, When Administered as Intramuscular Injection to Healthy Children 15 Months to 6 Years of Age
GlaxoSmithKline
- Location
- Simpsonville, SC + 14 other US sites
- Eligibility basics
- Ages 1–6
- RecruitingHealthy volunteersPhase 3
A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age
GlaxoSmithKline
- Location
- Charleston, SC + 46 other US sites
- Eligibility basics
- Ages 1–1
- RecruitingHealthy volunteers
Helix Research Network
Helix, Inc
- Location
- Charleston, SC + 13 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Caris Biorepository Research Protocol
Caris Science, Inc.
- Location
- Charleston, SC + 37 other US sites
- Eligibility basics
- Ages 18+