Mental health · South Carolina
Mental health studies in South Carolina
19 studies have at least one recruiting site in South Carolina. Mental health research includes studies of depression, anxiety, PTSD, bipolar disorder, schizophrenia and ADHD, testing medicines, devices and talk therapies.
19 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteers
Observational Study of Decentralized Urine Optical Interaction Patterns Associated With Environmental Microplastic and Nanoplastic Exposure
Ecotera Health LLC
- Location
- Charleston, SC + 50 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)
Definium Therapeutics US, Inc.
- Location
- North Charleston, SC + 22 other US sites
- Eligibility basics
- Ages 18–74
- Recruiting
A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With…
LivaNova
- Location
- Charleston, SC + 49 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
Abbott Medical Devices
- Location
- Charleston, SC + 24 other US sites
- Eligibility basics
- Ages 22–70
- RecruitingPhase 3
Forward Treatment of Attention Deficit and Hyperactivity Using Solriamfetol (FOCUS-2)
Axsome Therapeutics, Inc.
- Location
- North Charleston, SC + 28 other US sites
- Eligibility basics
- Ages 6–11
- RecruitingPhase 3
Forward Treatment of Attention Deficit and Hyperactivity Using Solriamfetol (FOCUS-3)
Axsome Therapeutics, Inc.
- Location
- North Charleston, SC + 27 other US sites
- Eligibility basics
- Ages 12–17
- RecruitingPhase 2
A Study to Evaluate Safety and Efficacy of ALKS 7290 Compared With Placebo in Adult Participants With Attention Deficit Hyperactivity Disorder (ALKS 7290-201)
Alkermes, Inc.
- Location
- North Charleston, SC + 17 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 4
Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD
Supernus Pharmaceuticals, Inc.
- Location
- North Charleston, SC + 38 other US sites
- Eligibility basics
- Ages 4–5
- RecruitingPhase 2
A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis
MapLight Therapeutics
- Location
- Port Royal, SC + 32 other US sites
- Eligibility basics
- Ages 55–90
- Recruiting
SAINT in Postpartum Depression (PPD)
Magnus Medical
- Location
- Charleston, SC + 3 other US sites
- Eligibility basics
- Ages 18–45 · Women only
- RecruitingPhase 3
Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms
Janssen Research & Development, LLC
- Location
- Charleston, SC + 41 other US sites
- Eligibility basics
- Ages 18–74
- RecruitingPhase 2
A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)
Tonix Pharmaceuticals, Inc.
- Location
- North Charleston, SC + 25 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder
AbbVie
- Location
- Charleston, SC + 46 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteers
COPEWeb Training for Providers
VA Office of Research and Development
- Location
- Charleston, SC
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
RECOVERS - Realigning Emotion and COgnition Via prEcision Regulation networkS
Medical University of South Carolina
- Location
- Charleston, SC
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteers
Digitally Enhanced Stepped-Care for Depression in Primary Care
Medical University of South Carolina
- Location
- Charleston, SC
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 4
Atomoxetine and Executive Function in PTSD
VA Office of Research and Development
- Location
- Charleston, SC
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteers
A Pilot Study of a Remote ADHD Monitoring Program
IDeA States Pediatric Clinical Trials Network
- Location
- Charleston, SC + 1 other US site
- Eligibility basics
- Ages 5–11
- RecruitingHealthy volunteers
Implementation Supports for Improving Identification and Delivery of School-based Mental Health Supports for Middle Schools Students
University of Virginia
- Location
- Columbia, SC + 2 other US sites
- Eligibility basics
- Ages 10–99
Who these studies look for
Studies usually require a confirmed diagnosis and stable circumstances, and they monitor safety closely. If you are in crisis, contact a crisis line or emergency services rather than a study.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Will joining affect my current treatment?
Some studies require changes to medicines, which the study team manages; others add to your usual care. Talk to your own clinician before making any change.