Vaccine · Texas
Vaccine studies in Texas
26 studies have at least one recruiting site in Texas. Vaccine trials test how well new or updated vaccines produce an immune response and how they are tolerated. Many recruit healthy adults; some focus on older adults, children or people with specific conditions.
26 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1
A Clinical Trial to Look at the Safety and Immune Responses of the RNA-based Vaccine BNT168 in Adults Living With or Without HIV
BioNTech SE
- Location
- Houston, TX
- Eligibility basics
- Ages 18–50
- RecruitingHealthy volunteersPhase 1/Phase 2
Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older
Sanofi
- Location
- Austin, TX + 49 other US sites
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteersPhase 1
A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)
Merck Sharp & Dohme LLC
- Location
- Carrollton, TX + 14 other US sites
- Eligibility basics
- Ages 2 mo–1
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study on the Safety and Immune Response of a Urinary Tract Infection (UTI) Vaccine in Adults 18-64 Years of Age and Clinical Efficacy in Females 18-64 Years of Age
GlaxoSmithKline
- Location
- Weatherford, TX + 5 other US sites
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteersPhase 1
Safety and Immunogenicity of a Self-Amplifying RNA Vaccine Against Crimean-Congo Hemorrhagic Fever
HDT Bio
- Location
- San Antonio, TX
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteersPhase 1
A Safety and Immunogenicity Trial of OCU500, ChAd36 Vector Encoding SARS-CoV-2 Spike Vaccine Via Intranasal and Inhalational Routes in Previously Vaccinated Adults
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Galveston, TX + 4 other US sites
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteersPhase 1
Thymalfasin (Thymosin Alpha 1; Ta1) as an Enhancer of Vaccine Response Among Older Adults Receiving Booster Doses of COVID-19 Vaccine
The Methodist Hospital Research Institute
- Location
- Houston, TX
- Eligibility basics
- Ages 65–100
- RecruitingHealthy volunteersPhase 3
A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.
Pfizer
- Location
- Brownsville, TX + 101 other US sites
- Eligibility basics
- Ages 1 mo–7 mo
- RecruitingHealthy volunteersPhase 4
Study of a Recombinant Spike COVID-19 Vaccine With Matrix-M in Older Adults and People at Increased Risk of Severe COVID-19
Sanofi
- Location
- Austin, TX + 19 other US sites
- Eligibility basics
- Ages 12+
- RecruitingHealthy volunteersPhase 3
A Phase 3 Study of Revaccination in Subsequent Pregnancies With Bivalent RSV Vaccine and Duration of Protection of a Single Dose
Pfizer
- Location
- Houston, TX + 76 other US sites
- Eligibility basics
- Ages 0 mo+
- RecruitingHealthy volunteersPhase 3
A Study to Assess the Safety, Tolerability, and Immunogenicity of 3 Lots of a Multivalent Pneumococcal Conjugate Vaccine Administered to Adults
Pfizer
- Location
- Mesquite, TX + 36 other US sites
- Eligibility basics
- Ages 18–49
- RecruitingHealthy volunteersPhase 3
A Study to Evaluate the Immune Response and Safety of a Vaccine Against Influenza in Adults 18-64 Years of Age
GlaxoSmithKline
- Location
- DeSoto, TX + 11 other US sites
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteersPhase 3
Lot-to-lot Consistency Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From 2 Months of Age
Sanofi
- Location
- Edinburg, TX + 13 other US sites
- Eligibility basics
- Ages 1 mo–2 mo
- RecruitingHealthy volunteersPhase 3
A Study of COVID-19 Vaccine(s) in Children and Adults
BioNTech SE
- Location
- Dallas, TX + 13 other US sites
- Eligibility basics
- Ages 5+
- RecruitingHealthy volunteersPhase 3
Study to Learn About Safety, Tolerability, and Immune Response of a Catch-up Pneumococcal Vaccine in Children and Adolescents
Pfizer
- Location
- Corpus Christi, TX + 49 other US sites
- Eligibility basics
- Ages 1–17
- RecruitingHealthy volunteersPhase 3
A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps, Rubella and Varicella Vaccine, When Administered as Intramuscular Injection to Healthy Children 15 Months to 6 Years of Age
GlaxoSmithKline
- Location
- Frisco, TX + 14 other US sites
- Eligibility basics
- Ages 1–6
- RecruitingHealthy volunteersPhase 3
A Study on the Safety of an Investigational Chickenpox Vaccine, When Given to Healthy Children, 12 to 15 Months of Age
GlaxoSmithKline
- Location
- Dallas, TX + 14 other US sites
- Eligibility basics
- Ages 1–1
- RecruitingHealthy volunteersPhase 3
A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age
GlaxoSmithKline
- Location
- Beaumont, TX + 46 other US sites
- Eligibility basics
- Ages 1–1
- RecruitingHealthy volunteersPhase 3
A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine and a Marketed Measles, Mumps and Rubella Vaccine When Administered as Intramuscular Injection to Healthy Children 12 to 15 Months of Age
GlaxoSmithKline
- Location
- Houston, TX + 12 other US sites
- Eligibility basics
- Ages 1–1
- RecruitingHealthy volunteersPhase 2
A Study to Learn About mRNA Vaccines Against Influenza in Adults
Pfizer
- Location
- Mesquite, TX + 14 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Learn About Revaccination With a Vaccine Called RSVpreF in Immunocompromised Adults
Pfizer
- Location
- DeSoto, TX + 12 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne
Sanofi Pasteur, a Sanofi Company
- Location
- Baytown, TX + 78 other US sites
- Eligibility basics
- Ages 18–45
- RecruitingPhase 1
A Study on the Safety and Immune Response of Investigational mRNA Seasonal Flu/COVID-19 Combination Vaccine in Adults
GlaxoSmithKline
- Location
- Austin, TX + 11 other US sites
- Eligibility basics
- Ages 65–85
- RecruitingPhase 3
Study of a Single Dose of a 21-valent Pneumococcal Conjugate Vaccine in Children and Adolescents With Sickle Cell Disease
Sanofi
- Location
- Houston, TX + 4 other US sites
- Eligibility basics
- Ages 2–17
Who these studies look for
Vaccine studies often exclude people who recently received a related vaccine or had the infection, and those with conditions or medicines that affect the immune system.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Could I receive a placebo?
Often yes. Many vaccine trials are randomized, so some participants receive a comparison vaccine or placebo. The consent document explains this.