Study type
Pain studies recruiting now
Pain research covers chronic back pain, fibromyalgia, nerve pain and short-term pain after procedures, testing medicines, devices and non-drug approaches.
115 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingHealthy volunteers
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
Brown University
- Location
- Providence, RI
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
COA-APTIC Cognitive Interview Study of Caregiver and Clinician Assessment of Acute Pain in Infants and Young Children
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Cryoablation Effects on Acute and Chronic Pain After Thoracotomy and Thoracoscopy
University of Michigan
- Location
- Ann Arbor, MI
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Self-management of Low Back Pain in Horticulture Workers
University of Florida
- Location
- Gainesville, FL
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
E-Tailored Pain Management Support for Dementia Family Caregivers: Feasibility of the PACE-app
University of Iowa
- Location
- Iowa City, IA
- Eligibility basics
- Ages 18–100
- RecruitingHealthy volunteers
Empathy Through Pain Control: Lidocaine Paracervical Block for IUD Placements
University of California, San Diego
- Location
- La Jolla, CA
- Eligibility basics
- Ages 18–50 · Women only
- RecruitingHealthy volunteers
TENS Unit for Analgesia During IUD Insertion
Tufts Medical Center
- Location
- Boston, MA
- Eligibility basics
- Ages 12–50 · Women only
- RecruitingHealthy volunteersPhase 2
Valacyclovir in Pain Management of Acute Apical Abscesses
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 4
The Effect of Outpatient Ketamine Infusion on Chronic Neuropathic Pain and PTSD
Margaux M. Salas, PhD
- Location
- San Antonio, TX
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteers
Upper and Lower Extremity Exercise and Exercise-Induced Hypoalgesia in Knee Osteoarthritis
University of Texas, El Paso
- Location
- El Paso, TX
- Eligibility basics
- Ages 45–90
- RecruitingHealthy volunteersPhase 2
Effects of Oral Tranexamic Acid Following Total Knee Arthroplasty
Matthew Grosso, MD
- Location
- Hartford, CT
- Eligibility basics
- Ages 18–89
- RecruitingHealthy volunteers
Focused Ultrasound for the Complex Patient
Washington D.C. Veterans Affairs Medical Center
- Location
- Washington D.C., DC
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 4
Liposomal Bupivacaine Vs Bupivacaine with Dexmedetomidine in Erector Spinae Plane Blocks for Mastectomies
United States Naval Medical Center, Portsmouth
- Location
- Portsmouth, VA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Embo Registry; National Registry for Artery Embolization
Vascular Solutions of North Carolina
- Location
- Cary, NC + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
PRECISION Pain Research Registry
University of North Texas Health Science Center
- Location
- Fort Worth, TX
- Eligibility basics
- Ages 21–79
- RecruitingHealthy volunteers
REFINE Study: A Study In a Novel Interspinous Fusion Device In Subjects With Low Back Pain
Pacific Research Institute
- Location
- Jupiter, FL + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 4
Trigger Point Injection for Myofascial Pain Syndrome in the Low Back: A Randomized Controlled Trial
Madigan Army Medical Center
- Location
- Tacoma, WA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 4
Optimizing Pain Control in Transurethral Resection of the Prostate
Benaroya Research Institute
- Location
- Seattle, WA
- Eligibility basics
- Ages 18+ · Men only
- RecruitingHealthy volunteersPhase 4
Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy
Children's Healthcare of Atlanta
- Location
- Atlanta, GA
- Eligibility basics
- Ages 3–18
Who these studies look for
Studies usually set a pain score range and limits on pain medicines. Some short-term pain studies involve a scheduled minor procedure.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
What is an acute pain study?
Some studies measure pain relief after a planned minor procedure, such as dental surgery or bunion removal, performed as part of the study. Each listing describes what is involved.