Older adults · California
Studies for adults 50 and older in California
These studies set a minimum age of 50 or older in their official record. Many look at conditions more common with age, and some vaccine and memory studies specifically need older participants.
117 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1
A Study of V132 in Healthy Older Participants (V132-001)
Merck Sharp & Dohme LLC
- Location
- Anaheim, CA + 9 other US sites
- Eligibility basics
- Ages 50–75
- RecruitingHealthy volunteersPhase 1/Phase 2
Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older
Sanofi
- Location
- Huntington Beach, CA + 49 other US sites
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteersPhase 1
Renal Impairment Study for Oral EC5026
EicOsis Human Health Inc.
- Location
- Sacramento, CA
- Eligibility basics
- Ages 55+
- RecruitingHealthy volunteersPhase 1
Writing About Experiences and Health in Older Adults II
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteersPhase 1
Safety and Tolerability Trial of Psilocybin in Healthy Older Adults
University of Colorado, Denver
- Location
- San Francisco, CA + 5 other US sites
- Eligibility basics
- Ages 65–85
- RecruitingHealthy volunteersPhase 1
A Study of Psychedelics in Healthy Older Adults With Low Well-being
Jennifer Mitchell
- Location
- San Francisco, CA
- Eligibility basics
- Ages 50–85
- RecruitingHealthy volunteersPhase 1
TREAD: Time Restricted Eating Intervention for Alzheimer's Disease
University of California, San Diego
- Location
- San Diego, CA
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteersPhase 1/Phase 2
FACE Phase II (a Stage II Trial)
Stanford University
- Location
- Palo Alto, CA
- Eligibility basics
- Ages 60–89
- RecruitingHealthy volunteersPhase 1
Investigating the Persisting Effects of a Single Dose of Psilocybin on Structural Plasticity in Healthy Older Adults
University of California, Berkeley
- Location
- Berkeley, CA
- Eligibility basics
- Ages 60–85
- RecruitingHealthy volunteersPhase 1
CogT pSOPT Intervention Study
Stanford University
- Location
- Palo Alto, CA
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteers
Galleri® in the Medicare Population.
GRAIL, Inc.
- Location
- Auburn, CA + 70 other US sites
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteersPhase 3
A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older
Pfizer
- Location
- Daly City, CA + 138 other US sites
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
BoxX-NoAF Clinical Trial
AtriCure, Inc.
- Location
- San Diego, CA + 30 other US sites
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
ProACT Post-Approval Study
Uromedica
- Location
- Los Angeles, CA + 13 other US sites
- Eligibility basics
- Ages 50+ · Men only
- RecruitingHealthy volunteers
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
Cleerly, Inc.
- Location
- Beverly Hills, CA + 121 other US sites
- Eligibility basics
- Ages 55+
- RecruitingHealthy volunteersPhase 3
A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age
GlaxoSmithKline
- Location
- Dublin, CA + 130 other US sites
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
Immune Defense Protein Impact On Respiratory Immune Outcomes
Quantec Ltd
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 60+
- RecruitingPhase 3
[18F]PI-2620 Phase 3 Histopathological Study
Lantheus Biosciences Ltd.
- Location
- Los Angeles, CA + 16 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular…
AbbVie
- Location
- Campbell, CA + 54 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2
A Study to Investigate the Safety and Effectiveness of SAR448851 in Participants With Early Alzheimer's Disease
Sanofi
- Location
- Long Beach, CA + 9 other US sites
- Eligibility basics
- Ages 55–85
- RecruitingPhase 2
A Phase 2 Efficacy and Safety Study of GAL-101, 2% Ophthalmic Solution in Non-foveal Geographic Atrophy Secondary to Non-neovascular AMD
Galimedix Therapeutics Inc
- Location
- Beverly Hills, CA + 1 other US site
- Eligibility basics
- Ages 55+
- RecruitingPhase 3
Sarilumab Efficacy and Safety in Adults With Early Polymyalgia Rheumatica
Sanofi
- Location
- Covina, CA + 46 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2
A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)
Merck Sharp & Dohme LLC
- Location
- Irvine, CA + 34 other US sites
- Eligibility basics
- Ages 50–85
- RecruitingPhase 1/Phase 2
A Safety and Efficacy Study of a One-time Intravitreal Injection of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration
Sanofi
- Location
- Beverly Hills, CA + 30 other US sites
- Eligibility basics
- Ages 60+