Who can join
Studies for adults 50 and older
These studies set a minimum age of 50 or older in their official record. Many look at conditions more common with age, and some vaccine and memory studies specifically need older participants.
417 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1
A Study of V132 in Healthy Older Participants (V132-001)
Merck Sharp & Dohme LLC
- Location
- Anaheim, CA + 9 other US sites
- Eligibility basics
- Ages 50–75
- RecruitingHealthy volunteersPhase 1/Phase 2
Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older
Sanofi
- Location
- Gadsden, AL + 49 other US sites
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteersPhase 1/Phase 2
Digital STEADI Efficacy
Friendi.fi Corporation
- Location
- Atlanta, GA
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteersPhase 1
Safety and Pharmacokinetics of ALZ-507 in Healthy Elderly Adults
Alzheon Inc.
- Location
- Miami, FL
- Eligibility basics
- Ages 50–75
- RecruitingHealthy volunteersPhase 1
A Study to Assess the Adverse Events and How Oral Emraclidine Moves Through the Body of Healthy Elderly Adult Participants
AbbVie
- Location
- Maitland, FL + 3 other US sites
- Eligibility basics
- Ages 65–85
- RecruitingHealthy volunteersPhase 1
Renal Impairment Study for Oral EC5026
EicOsis Human Health Inc.
- Location
- Sacramento, CA
- Eligibility basics
- Ages 55+
- RecruitingHealthy volunteersEarly Phase 1
Evaluation of [¹⁸F]MODAG-009 PET Imaging in Synucleinopathies
MODAG GmbH
- Location
- New Haven, CT
- Eligibility basics
- Ages 50–80
- RecruitingHealthy volunteersPhase 1
Safety and Immunogenicity Study of Revaccination With SCB-1019T in Healthy Adults
Clover Biopharmaceuticals USA, LLC
- Location
- Phoenix, AZ + 4 other US sites
- Eligibility basics
- Ages 60–85
- RecruitingHealthy volunteersPhase 1
Exploratory Clinical Study to Assess Safety and Efficacy of Xenon Gas Inhalation to Control Neuroinflammation
General Biophysics LLC
- Location
- Boston, MA
- Eligibility basics
- Ages 55–75
- RecruitingHealthy volunteersPhase 1
PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)
National Institute of Mental Health (NIMH)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 50–100
- RecruitingHealthy volunteersPhase 2Overnight stay mentioned
Neuroplasticity Enhancement From Cognitive Training Reinforced by Psilocybin
National Institute on Aging (NIA)
- Location
- Baltimore, MD
- Eligibility basics
- Ages 65–120
- RecruitingHealthy volunteersPhase 1/Phase 2
SV2A in Older Adults
Yale University
- Location
- New Haven, CT
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteersPhase 1
Writing About Experiences and Health in Older Adults II
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteersPhase 1
The Gut - PRO Study
University of Wisconsin, Madison
- Location
- Madison, WI
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteersPhase 1
Safety and Tolerability Trial of Psilocybin in Healthy Older Adults
University of Colorado, Denver
- Location
- San Francisco, CA + 5 other US sites
- Eligibility basics
- Ages 65–85
- RecruitingHealthy volunteersPhase 1
A Study of Psychedelics in Healthy Older Adults With Low Well-being
Jennifer Mitchell
- Location
- San Francisco, CA
- Eligibility basics
- Ages 50–85
- RecruitingHealthy volunteersEarly Phase 1
LpD3.5 Intervention Study in Older Adults- LISA-I Trial
University of South Florida
- Location
- Tampa, FL
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteersPhase 1
UAB Alzheimer's Disease Center Core Cohort - Tau Imaging Substudy
University of Alabama at Birmingham
- Location
- Birmingham, AL
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteersOvernight stay mentioned
The Osteoarthritis Prevention Study
Wake Forest University
- Location
- Boston, MA + 1 other US site
- Eligibility basics
- Ages 50+ · Women only
- RecruitingHealthy volunteersEarly Phase 1
PK/PD of Oral and Vaporized Delta-9-Tetrahydrocannabinol (THC) in Older Adults
Yale University
- Location
- West Haven, CT
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteersPhase 1
Thymalfasin (Thymosin Alpha 1; Ta1) as an Enhancer of Vaccine Response Among Older Adults Receiving Booster Doses of COVID-19 Vaccine
The Methodist Hospital Research Institute
- Location
- Houston, TX
- Eligibility basics
- Ages 65–100
- RecruitingHealthy volunteersPhase 1/Phase 2
Aging and Task-specific Training to Reduce Falls
University of Illinois at Chicago
- Location
- Chicago, IL
- Eligibility basics
- Ages 60–90
- RecruitingHealthy volunteersPhase 1/Phase 2
MTOR Inhibitors in Older Adults
University of Texas Southwestern Medical Center
- Location
- Dallas, TX
- Eligibility basics
- Ages 65–80
- RecruitingHealthy volunteersEarly Phase 1
Impact of Nrf2 Activation on Macrovascular, Microvascular & Leg Function & Walking Capacity in Peripheral Artery Disease
University of Nebraska
- Location
- Omaha, NE
- Eligibility basics
- Ages 50–75
Questions
If I fit this group, will I qualify?
Not necessarily. Age and sex limits are only the first filter. Each study has its own inclusion and exclusion criteria, and the research team decides at screening.
Where do these age and sex limits come from?
From the eligibility section of each study’s official ClinicalTrials.gov record. We don’t infer eligibility from anything else.