Older adults · Illinois
Studies for adults 50 and older in Illinois
These studies set a minimum age of 50 or older in their official record. Many look at conditions more common with age, and some vaccine and memory studies specifically need older participants.
48 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1/Phase 2
Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older
Sanofi
- Location
- Melrose Park, IL + 49 other US sites
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteersPhase 1
A Study to Assess the Adverse Events and How Oral Emraclidine Moves Through the Body of Healthy Elderly Adult Participants
AbbVie
- Location
- Grayslake, IL + 3 other US sites
- Eligibility basics
- Ages 65–85
- RecruitingHealthy volunteersPhase 1/Phase 2
Aging and Task-specific Training to Reduce Falls
University of Illinois at Chicago
- Location
- Chicago, IL
- Eligibility basics
- Ages 60–90
- RecruitingHealthy volunteersPhase 3
A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older
Pfizer
- Location
- Melrose Park, IL + 138 other US sites
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
BoxX-NoAF Clinical Trial
AtriCure, Inc.
- Location
- Chicago, IL + 30 other US sites
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
Cleerly, Inc.
- Location
- Chicago, IL + 121 other US sites
- Eligibility basics
- Ages 55+
- RecruitingHealthy volunteersPhase 3
A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age
GlaxoSmithKline
- Location
- Chicago, IL + 130 other US sites
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
Falcon Real World Evidence Registry
Exact Sciences Corporation
- Location
- Evanston, IL + 1 other US site
- Eligibility basics
- Ages 50–80
- RecruitingHealthy volunteers
Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment…
GAP Innovations, PBC
- Location
- Chicago, IL + 18 other US sites
- Eligibility basics
- Ages 60–90
- RecruitingHealthy volunteers
InSpace Accelerated Rehabilitation Study
Stryker Endoscopy
- Location
- Chicago, IL + 10 other US sites
- Eligibility basics
- Ages 65+
- RecruitingPhase 3
Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular…
AbbVie
- Location
- Oak Lawn, IL + 54 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
Sarilumab Efficacy and Safety in Adults With Early Polymyalgia Rheumatica
Sanofi
- Location
- Willowbrook, IL + 46 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2
A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)
Merck Sharp & Dohme LLC
- Location
- Elk Grove Village, IL + 34 other US sites
- Eligibility basics
- Ages 50–85
- RecruitingPhase 1/Phase 2
A Safety and Efficacy Study of a One-time Intravitreal Injection of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration
Sanofi
- Location
- Lemont, IL + 30 other US sites
- Eligibility basics
- Ages 60+
- RecruitingPhase 3
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
Hoffmann-La Roche
- Location
- Chicago, IL + 67 other US sites
- Eligibility basics
- Ages 50–90
- RecruitingPhase 4
A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)
Alpha Cognition, Inc
- Location
- Northbrook, IL + 21 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration
Amgen
- Location
- Chicago, IL + 54 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
Regeneron Pharmaceuticals
- Location
- Chicago, IL + 144 other US sites
- Eligibility basics
- Ages 50–85
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
Bristol-Myers Squibb
- Location
- Chicago, IL + 22 other US sites
- Eligibility basics
- Ages 60–85
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
Bristol-Myers Squibb
- Location
- Chicago, IL + 23 other US sites
- Eligibility basics
- Ages 60–85
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease
Hoffmann-La Roche
- Location
- Chicago, IL + 52 other US sites
- Eligibility basics
- Ages 50–85
- RecruitingPhase 2/Phase 3
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
EyeBiotech Ltd.
- Location
- Oak Park, IL + 66 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2/Phase 3
A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
Janssen Research & Development, LLC
- Location
- Lemont, IL + 44 other US sites
- Eligibility basics
- Ages 60+
- RecruitingPhase 2
Phase 2, Efficacy and Safety Study of ACP-204 in Lewy Body Dementia Psychosis
ACADIA Pharmaceuticals Inc.
- Location
- Chicago, IL + 27 other US sites
- Eligibility basics
- Ages 55–84