Older adults · Missouri
Studies for adults 50 and older in Missouri
These studies set a minimum age of 50 or older in their official record. Many look at conditions more common with age, and some vaccine and memory studies specifically need older participants.
40 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1
A Study of V132 in Healthy Older Participants (V132-001)
Merck Sharp & Dohme LLC
- Location
- Springfield, MO + 9 other US sites
- Eligibility basics
- Ages 50–75
- RecruitingHealthy volunteersPhase 1
Safety and Immunogenicity Study of Revaccination With SCB-1019T in Healthy Adults
Clover Biopharmaceuticals USA, LLC
- Location
- Kansas City, MO + 4 other US sites
- Eligibility basics
- Ages 60–85
- RecruitingHealthy volunteers
Galleri® in the Medicare Population.
GRAIL, Inc.
- Location
- Joplin, MO + 70 other US sites
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteersPhase 3
A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older
Pfizer
- Location
- St Louis, MO + 138 other US sites
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
BoxX-NoAF Clinical Trial
AtriCure, Inc.
- Location
- St Louis, MO + 30 other US sites
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
Cleerly, Inc.
- Location
- St Louis, MO + 121 other US sites
- Eligibility basics
- Ages 55+
- RecruitingHealthy volunteersPhase 3
A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age
GlaxoSmithKline
- Location
- Chesterfield, MO + 130 other US sites
- Eligibility basics
- Ages 65+
- RecruitingPhase 3
Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular…
AbbVie
- Location
- St Louis, MO + 54 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
Sarilumab Efficacy and Safety in Adults With Early Polymyalgia Rheumatica
Sanofi
- Location
- St Louis, MO + 46 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2/Phase 3
ACP-204 in Adults With Alzheimer's Disease Psychosis
ACADIA Pharmaceuticals Inc.
- Location
- St Louis, MO + 34 other US sites
- Eligibility basics
- Ages 55–95
- RecruitingPhase 3
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
Hoffmann-La Roche
- Location
- St Louis, MO + 67 other US sites
- Eligibility basics
- Ages 50–90
- RecruitingPhase 4
A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)
Alpha Cognition, Inc
- Location
- St Louis, MO + 21 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2
A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette);
Genentech, Inc.
- Location
- St Louis, MO + 14 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration
Amgen
- Location
- St Louis, MO + 54 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
Regeneron Pharmaceuticals
- Location
- St Louis, MO + 144 other US sites
- Eligibility basics
- Ages 50–85
- RecruitingPhase 2
A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
Eli Lilly and Company
- Location
- Bolivar, MO + 29 other US sites
- Eligibility basics
- Ages 55–85
- RecruitingPhase 2
Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
Lighthouse Pharmaceuticals, Inc.
- Location
- Chesterfield, MO + 36 other US sites
- Eligibility basics
- Ages 55–80
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease
Hoffmann-La Roche
- Location
- St Louis, MO + 52 other US sites
- Eligibility basics
- Ages 50–85
- RecruitingPhase 2/Phase 3
A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
Janssen Research & Development, LLC
- Location
- St Louis, MO + 44 other US sites
- Eligibility basics
- Ages 60+
- RecruitingPhase 3
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- Location
- St Louis, MO + 43 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 2
Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD
ONL Therapeutics
- Location
- St Louis, MO + 55 other US sites
- Eligibility basics
- Ages 55+
- RecruitingPhase 3
Efficacy and Safety of Intranasal Cenegermin in Adult Participants With Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)
Dompé Farmaceutici S.p.A
- Location
- St Louis, MO + 13 other US sites
- Eligibility basics
- Ages 50–80
- RecruitingPhase 3
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)
Anthos Therapeutics, Inc.
- Location
- Kansa City, MO + 131 other US sites
- Eligibility basics
- Ages 65+
- RecruitingPhase 3
A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).
Eli Lilly and Company
- Location
- Bolivar, MO + 41 other US sites
- Eligibility basics
- Ages 55+