Older adults · Tennessee
Studies for adults 50 and older in Tennessee
These studies set a minimum age of 50 or older in their official record. Many look at conditions more common with age, and some vaccine and memory studies specifically need older participants.
30 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1
Safety and Immunogenicity Study of Revaccination With SCB-1019T in Healthy Adults
Clover Biopharmaceuticals USA, LLC
- Location
- Knoxville, TN + 4 other US sites
- Eligibility basics
- Ages 60–85
- RecruitingHealthy volunteersEarly Phase 1
Attentional Mechanisms in SCD
Vanderbilt University Medical Center
- Location
- Nashville, TN
- Eligibility basics
- Ages 55+
- RecruitingHealthy volunteers
Galleri® in the Medicare Population.
GRAIL, Inc.
- Location
- Brentwood, TN + 70 other US sites
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteers
BoxX-NoAF Clinical Trial
AtriCure, Inc.
- Location
- Nashville, TN + 30 other US sites
- Eligibility basics
- Ages 65+
- RecruitingPhase 3
Sarilumab Efficacy and Safety in Adults With Early Polymyalgia Rheumatica
Sanofi
- Location
- Jackson, TN + 46 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
Hoffmann-La Roche
- Location
- Knoxville, TN + 67 other US sites
- Eligibility basics
- Ages 50–90
- RecruitingPhase 4
A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)
Alpha Cognition, Inc
- Location
- Cordova, TN + 21 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2
A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette);
Genentech, Inc.
- Location
- Nashville, TN + 14 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration
Amgen
- Location
- Nashville, TN + 54 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2
Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
Lighthouse Pharmaceuticals, Inc.
- Location
- Nashville, TN + 36 other US sites
- Eligibility basics
- Ages 55–80
- RecruitingPhase 2
Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease
Celgene
- Location
- Cordova, TN + 31 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
Bristol-Myers Squibb
- Location
- Cordova, TN + 23 other US sites
- Eligibility basics
- Ages 60–85
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease
Hoffmann-La Roche
- Location
- Memphis, TN + 52 other US sites
- Eligibility basics
- Ages 50–85
- RecruitingPhase 2/Phase 3
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
EyeBiotech Ltd.
- Location
- Germantown, TN + 66 other US sites
- Eligibility basics
- Ages 50+
- Recruiting
Post-Market Study to Assess iTind Safety in Comparison to UroLift
Olympus Corporation of the Americas
- Location
- Germantown, TN + 10 other US sites
- Eligibility basics
- Ages 50+ · Men only
- RecruitingPhase 2
Randomized Study to Evaluate the Effect of Obicetrapib in Participants With Preclinical Alzheimer's Disease
NewAmsterdam Pharma
- Location
- Nashville, TN
- Eligibility basics
- Ages 55–85
- RecruitingPhase 3
Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)
Adverum Biotechnologies, Inc.
- Location
- Nashville, TN + 78 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- Location
- Nashville, TN + 43 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 1/Phase 2
A Study to Assess the Safety and Effects of ABBV-1758 Following Subcutaneous or Intravenous Injections in Participants With Alzheimer's Disease
AbbVie
- Location
- Cordova, TN + 10 other US sites
- Eligibility basics
- Ages 50–90
- RecruitingPhase 2
Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD
ONL Therapeutics
- Location
- Nashville, TN + 55 other US sites
- Eligibility basics
- Ages 55+
- RecruitingPhase 1/Phase 2
4D-150 in Patients With Neovascular (Wet) Age-Related Macular Degeneration
4D Molecular Therapeutics
- Location
- Nashville, TN + 19 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2/Phase 3
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)
EyeBiotech Ltd.
- Location
- Hixson, TN + 51 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2/Phase 3
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study
Kardigan, Inc.
- Location
- Nashville, TN + 46 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2
A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in…
Apellis Pharmaceuticals, Inc.
- Location
- Nashville, TN + 77 other US sites
- Eligibility basics
- Ages 60+