Location · Tennessee
Clinical trials recruiting in Tennessee
515 recruiting studies have at least one site in Tennessee; 118 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in Tennessee.
515 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1/Phase 2
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
Xencor, Inc.
- Location
- Cordova, TN + 27 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1/Phase 2
Study to Assess Safety and Immunogenicity of an Egg-based H5N8 Influenza Vaccine at Multiple Dose Levels Adjuvanted With Matrix-M in Healthy Participants 18 Years of Age and Above.
Sanofi
- Location
- Knoxville, TN + 15 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Novartis Pharmaceuticals
- Location
- Knoxville, TN + 18 other US sites
- Eligibility basics
- Ages 18–100
- RecruitingHealthy volunteersPhase 1
A First in Human Study of the Safety, Tolerability, and the Physiologically Based Pharmacokinetics of XFB19 in Healthy Adult Volunteers.
Xfibra, Inc.
- Location
- Knoxville, TN
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
A Study to Learn About a Vaccine Against E Coli in Healthy Adults
Pfizer
- Location
- Knoxville, TN + 9 other US sites
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteersPhase 1
A Safety Study of IVMED-85 Ophthalmic Solution in Healthy Adults
iVeena Delivery Systems, Inc.
- Location
- Memphis, TN
- Eligibility basics
- Ages 18–49
- RecruitingHealthy volunteersPhase 1/Phase 2
Study of VGA039 in Healthy Volunteers and Patients With Von Willebrand Disease (VIVID)
Vega Therapeutics, Inc
- Location
- Nashville, TN + 9 other US sites
- Eligibility basics
- Ages 12–60
- RecruitingHealthy volunteersPhase 1
Safety and Immunogenicity Study of Revaccination With SCB-1019T in Healthy Adults
Clover Biopharmaceuticals USA, LLC
- Location
- Knoxville, TN + 4 other US sites
- Eligibility basics
- Ages 60–85
- RecruitingHealthy volunteersPhase 1
Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Nashville, TN + 3 other US sites
- Eligibility basics
- Ages 18–60
- RecruitingHealthy volunteersPhase 1
A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Nashville, TN + 4 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
A Phase 1 Study of 99mTc-p5+14 in Healthy Volunteers and Patients With AL or ATTR Systemic Amyloidosis
University of Tennessee Graduate School of Medicine
- Location
- Knoxville, TN
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersEarly Phase 1
Attentional Mechanisms in SCD
Vanderbilt University Medical Center
- Location
- Nashville, TN
- Eligibility basics
- Ages 55+
- RecruitingHealthy volunteersPhase 1
TCRαβ-depleted Progenitor Cell Graft With Early Memory T-cell DLI, Plus Selected Use of Blinatumomab, in naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies
St. Jude Children's Research Hospital
- Location
- Memphis, TN
- Eligibility basics
- Up to age 21
- RecruitingHealthy volunteersPhase 1/Phase 2
Enhancing Parasympathetic Activity to Improve Endothelial Dysfunction, Vascular Oxidative Stress in African Americans
Vanderbilt University Medical Center
- Location
- Nashville, TN
- Eligibility basics
- Ages 18–60
- RecruitingHealthy volunteersPhase 1
Tranexamic Acid in Rhinoplasty: Perioperative Bleeding, Edema and Ecchymosis
Vanderbilt University Medical Center
- Location
- Nashville, TN
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersOvernight stay mentioned
Sickle Cell Disease and the Genomic and Gene Therapy Needs of Stakeholders
St. Jude Children's Research Hospital
- Location
- Memphis, TN
- Eligibility basics
- Ages 13+
- RecruitingHealthy volunteersPhase 1
[18F]F-DOPA Imaging in Patients With Autonomic Failure
Daniel Claassen
- Location
- Nashville, TN
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersEarly Phase 1
Cardiometabolic Benefit of Reducing Iatrogenic Hyperinsulinemia Using Insulin Adjunctive Therapy in Type 1 Diabetes
Vanderbilt University Medical Center
- Location
- Nashville, TN
- Eligibility basics
- Ages 18–60
- RecruitingHealthy volunteers
Prospective Multi-Center Trial for FemBloc Permanent Birth Control
Femasys Inc.
- Location
- Chattanooga, TN + 11 other US sites
- Eligibility basics
- Ages 21–50 · Women only
- RecruitingHealthy volunteers
Extensively Hydrolyzed Formula Growth Monitioring Study (GMS)
Mead Johnson Nutrition
- Location
- Memphis, TN + 9 other US sites
- Eligibility basics
- Ages 0 mo–0 mo
- RecruitingHealthy volunteersPhase 3
A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.
Pfizer
- Location
- Memphis, TN + 101 other US sites
- Eligibility basics
- Ages 1 mo–7 mo
- RecruitingHealthy volunteersPhase 3
A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
- Location
- Nashville, TN + 55 other US sites
- Eligibility basics
- Ages 18–79
- RecruitingHealthy volunteers
Galleri® in the Medicare Population.
GRAIL, Inc.
- Location
- Brentwood, TN + 70 other US sites
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteers
BoxX-NoAF Clinical Trial
AtriCure, Inc.
- Location
- Nashville, TN + 30 other US sites
- Eligibility basics
- Ages 65+