Mental health · Tennessee
Mental health studies in Tennessee
24 studies have at least one recruiting site in Tennessee. Mental health research includes studies of depression, anxiety, PTSD, bipolar disorder, schizophrenia and ADHD, testing medicines, devices and talk therapies.
24 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteers
Observational Study of Decentralized Urine Optical Interaction Patterns Associated With Environmental Microplastic and Nanoplastic Exposure
Ecotera Health LLC
- Location
- Nashville, TN + 50 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With…
LivaNova
- Location
- Brentwood, TN + 49 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Trial of the Efficacy and Safety of a Fixed Dose of SEP-363856 in Adults With Generalized Anxiety Disorder
Otsuka Pharmaceutical Development & Commercialization, Inc.
- Location
- Memphis, TN + 10 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)
Alpha Cognition, Inc
- Location
- Cordova, TN + 21 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol
Axsome Therapeutics, Inc.
- Location
- Memphis, TN + 35 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
Forward Treatment of Attention Deficit and Hyperactivity Using Solriamfetol (FOCUS-2)
Axsome Therapeutics, Inc.
- Location
- Memphis, TN + 28 other US sites
- Eligibility basics
- Ages 6–11
- RecruitingPhase 3
Forward Treatment of Attention Deficit and Hyperactivity Using Solriamfetol (FOCUS-3)
Axsome Therapeutics, Inc.
- Location
- Memphis, TN + 27 other US sites
- Eligibility basics
- Ages 12–17
- Recruiting
MaioRegen Prime Study for the Treatment of Deep Osteochondral Lesion of the Knee
Fin-Ceramica Faenza Spa
- Location
- Jackson, TN + 7 other US sites
- Eligibility basics
- Ages 18–60
- RecruitingPhase 4
Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD
Supernus Pharmaceuticals, Inc.
- Location
- Memphis, TN + 38 other US sites
- Eligibility basics
- Ages 4–5
- RecruitingPhase 3
Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder
Intra-Cellular Therapies, Inc.
- Location
- Nashville, TN + 46 other US sites
- Eligibility basics
- Ages 5–17
- RecruitingPhase 2
A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)
Tonix Pharmaceuticals, Inc.
- Location
- Mephis, TN + 25 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- Location
- Nashville, TN + 43 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 3
An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1)
Transcend Therapeutics
- Location
- Memphis, TN + 36 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
Syndeio Biosciences, Inc
- Location
- Franklin, TN + 22 other US sites
- Eligibility basics
- Ages 18–64
- Recruiting
Clinical Outcomes Study of the Nexel Total Elbow
Zimmer Biomet
- Location
- Germantown, TN + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study of NTX-1472 in Social Anxiety Disorder
Newleos Therapeutics, Inc.
- Location
- Memphis, TN + 9 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder
AbbVie
- Location
- Franklin, TN + 46 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive Disorder
AbbVie
- Location
- Memphis, TN + 32 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 4
A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
Axsome Therapeutics, Inc.
- Location
- Memphis, TN + 36 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteers
AI-Based Personalized Exercise Prescription Through Mobile Health on Physical Activity and Health Outcomes in Older Adults: A Feasibility Study
The University of Tennessee, Knoxville
- Location
- Knoxville, TN
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteersPhase 4
Characterization of the Serotonin 2A Receptor Selective PET Tracer [18F]MH.MZ in Patients With Neurodegenerative Diseases
Vanderbilt University Medical Center
- Location
- Nashville, TN
- Eligibility basics
- Ages 50–85
- RecruitingHealthy volunteers
NICU Utilization of Remote Voice Technology to Improve mateRnal Experience (NURTURE)
Vanderbilt University Medical Center
- Location
- Nashville, TN
- Eligibility basics
- Ages 18+ · Women only
- RecruitingHealthy volunteers
Precision Brain Stimulation to Reduce Cannabis Craving in Schizophrenia
Vanderbilt University Medical Center
- Location
- Nashville, TN
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteers
Latino Teen Depression Treatment Study
Duke University
- Location
- Nashville, TN
- Eligibility basics
- Ages 13+
Who these studies look for
Studies usually require a confirmed diagnosis and stable circumstances, and they monitor safety closely. If you are in crisis, contact a crisis line or emergency services rather than a study.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Will joining affect my current treatment?
Some studies require changes to medicines, which the study team manages; others add to your usual care. Talk to your own clinician before making any change.