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RecruitingAccepts healthy volunteersPhase 1

A Study to Learn About a Vaccine Against E Coli in Healthy Adults

Pfizer · NCT07122986

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–64 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Phase 1
Target enrollment
310
US sites recruiting
11
Study start
August 11, 2025
Record last updated
April 30, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study evaluates an investigational vaccine designed to protect against Escherichia coli (E coli). The primary objective is to assess the safety and tolerability of E coli vaccines administered intramuscularly to healthy adults.

Being studied: E coli vaccine 1 Dose A; E coli vaccine 1 Dose B; E coli vaccine 2; E coli vaccine 3; E coli Vaccine 4 Dose A; E coli Vaccine 4 Dose B; E coli Vaccine 4 Dose C; E coli Vaccine 5 Dose A; E coli Vaccine 5 Dose B; Placebo

Conditions: Healthy Participants

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Ages Eligible for Study: 18 to 64 Years (Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: Yes

Key Inclusion Criteria

  • Adult Participants >= 18 through \< 64 years of age at the time of enrollment.
  • Healthy participants as determined by medical history, physical examination, and clinical judgement of the investigator to be eligible for inclusion in the study.

Key Exclusion Criteria

  • Severe adverse reaction history associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) to any component of the study intervention(s).
  • Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination.
  • Women who are pregnant, plan to become pregnant during the study, or are breastfeeding.

Recruiting US locations

Study contacts (from the official record)

  • Pfizer CT.gov Call Center · 1-800-718-1021 · ClinicalTrials.gov_Inquiries@pfizer.com
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A Study to Learn About a Vaccine Against E Coli in Healthy Adults (NCT07122986) | Bored Studies