Who can join
Studies for adults 50 and older
These studies set a minimum age of 50 or older in their official record. Many look at conditions more common with age, and some vaccine and memory studies specifically need older participants.
417 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1/Phase 2
Post-operative Urinary Retention (POUR) Following Thoracic Surgery
Hackensack Meridian Health
- Location
- Hackensack, NJ
- Eligibility basics
- Ages 50+ · Men only
- RecruitingHealthy volunteersEarly Phase 1
Attentional Mechanisms in SCD
Vanderbilt University Medical Center
- Location
- Nashville, TN
- Eligibility basics
- Ages 55+
- RecruitingHealthy volunteersEarly Phase 1
RESTOR: PK/PD mTORi Inhibition in Older Adults
The University of Texas Health Science Center at San Antonio
- Location
- San Antonio, TX
- Eligibility basics
- Ages 65–90
- RecruitingHealthy volunteersPhase 1
Rapalog Pharmacology (RAP PAC) Study
University of Wisconsin, Madison
- Location
- Madison, WI
- Eligibility basics
- Ages 55–89
- RecruitingHealthy volunteersPhase 1
TREAD: Time Restricted Eating Intervention for Alzheimer's Disease
University of California, San Diego
- Location
- San Diego, CA
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteersEarly Phase 1
The Role of Occupational Therapy for Improving Medication Management for Persons With AMD, DR and Glaucoma
MCPHS University
- Location
- Worcester, MA
- Eligibility basics
- Ages 50–100
- RecruitingHealthy volunteersPhase 1/Phase 2
FACE Phase II (a Stage II Trial)
Stanford University
- Location
- Palo Alto, CA
- Eligibility basics
- Ages 60–89
- RecruitingHealthy volunteersEarly Phase 1
PET Imaging Evaluation of [11C]SY08
Massachusetts General Hospital
- Location
- Charlestown, MA
- Eligibility basics
- Ages 50–80
- RecruitingHealthy volunteersEarly Phase 1
Metformin and Muscle Recovery
University of Utah
- Location
- Salt Lake City, UT
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteersPhase 1/Phase 2
Assess Fibrin in Brains With AD/ADRD
Massachusetts General Hospital
- Location
- Boston, MA
- Eligibility basics
- Ages 55–90
- RecruitingHealthy volunteersPhase 1
Investigating the Persisting Effects of a Single Dose of Psilocybin on Structural Plasticity in Healthy Older Adults
University of California, Berkeley
- Location
- Berkeley, CA
- Eligibility basics
- Ages 60–85
- RecruitingHealthy volunteersOvernight stay mentioned
Inpatient Capture: A Mixed Methods Study to Develop an Inpatient Lung Cancer Screening Program in a Safety Net Hospital.
Physician Affiliate Group of New York
- Location
- New York, NY
- Eligibility basics
- Ages 50–80
- RecruitingHealthy volunteersPhase 1
CogT pSOPT Intervention Study
Stanford University
- Location
- Palo Alto, CA
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteers
Galleri® in the Medicare Population.
GRAIL, Inc.
- Location
- Fort Smith, AR + 70 other US sites
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteersPhase 3
A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older
Pfizer
- Location
- Athens, AL + 138 other US sites
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
BoxX-NoAF Clinical Trial
AtriCure, Inc.
- Location
- Scottsdale, AZ + 30 other US sites
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
ProACT Post-Approval Study
Uromedica
- Location
- Los Angeles, CA + 13 other US sites
- Eligibility basics
- Ages 50+ · Men only
- RecruitingHealthy volunteers
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
Cleerly, Inc.
- Location
- Chandler, AZ + 121 other US sites
- Eligibility basics
- Ages 55+
- RecruitingHealthy volunteersPhase 3
A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age
GlaxoSmithKline
- Location
- Anniston, AL + 130 other US sites
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
The Effects of Quercefit® and Ubiqsome™ in Mitigating Inflammation and Promoting Metabolic Health
Applied Science & Performance Institute
- Location
- Tampa, FL
- Eligibility basics
- Ages 50–75
- RecruitingHealthy volunteers
Falcon Real World Evidence Registry
Exact Sciences Corporation
- Location
- Evanston, IL + 1 other US site
- Eligibility basics
- Ages 50–80
- RecruitingHealthy volunteers
Data Collection Study Using CS (CardiacSense) BP (Blood Pressure) Watch and Pillow Systems
CardiacSense Ltd.
- Location
- Louisville, CO
- Eligibility basics
- Ages 50–80
- RecruitingHealthy volunteersPhase 3
Epidemiology and Biomarker Study in Alzheimer's Disease
Eli Lilly and Company
- Location
- Houston, TX
- Eligibility basics
- Ages 55–75
- RecruitingHealthy volunteers
Crownlands Observing Progression With Neurons Study
Crownlands
- Location
- Germantown, MD
- Eligibility basics
- Ages 55+
Questions
If I fit this group, will I qualify?
Not necessarily. Age and sex limits are only the first filter. Each study has its own inclusion and exclusion criteria, and the research team decides at screening.
Where do these age and sex limits come from?
From the eligibility section of each study’s official ClinicalTrials.gov record. We don’t infer eligibility from anything else.