Who can join
Studies for adults 50 and older
These studies set a minimum age of 50 or older in their official record. Many look at conditions more common with age, and some vaccine and memory studies specifically need older participants.
417 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteers
Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment…
GAP Innovations, PBC
- Location
- Atlantis, FL + 18 other US sites
- Eligibility basics
- Ages 60–90
- RecruitingHealthy volunteers
Immune Defense Protein Impact On Respiratory Immune Outcomes
Quantec Ltd
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteers
JDS-HF3.0 Supplementation on Menopause Related Quality of Life Outcomes in Postmenopausal Women
Bonafide Health
- Location
- Harrison, NY
- Eligibility basics
- Ages 50–70 · Women only
- RecruitingHealthy volunteers
US Benchmarking Clinical Study
eMyosound SAS
- Location
- Boston, MA + 2 other US sites
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteers
Pivotal Trial of an Automated AI-based System for Early Diagnosis and Prediction of Late Age-related Macular Degeneration
iHealthScreen Inc
- Location
- Richmond Hill, NY
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteers
InSpace Accelerated Rehabilitation Study
Stryker Endoscopy
- Location
- Phoenix, AZ + 10 other US sites
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy
Alzheimer's Light LLC
- Location
- Miami, FL
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteers
Longitudinal Cognitive Assessment by BoCA
Alzheimer's Light LLC
- Location
- Miami, FL
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
[18F]PI-2620 Phase 3 Histopathological Study
Lantheus Biosciences Ltd.
- Location
- Phoenix, AZ + 16 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular…
AbbVie
- Location
- Mesa, AZ + 54 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2
A Study to Investigate the Safety and Effectiveness of SAR448851 in Participants With Early Alzheimer's Disease
Sanofi
- Location
- Long Beach, CA + 9 other US sites
- Eligibility basics
- Ages 55–85
- RecruitingPhase 2
A Phase 2 Efficacy and Safety Study of GAL-101, 2% Ophthalmic Solution in Non-foveal Geographic Atrophy Secondary to Non-neovascular AMD
Galimedix Therapeutics Inc
- Location
- Beverly Hills, CA + 1 other US site
- Eligibility basics
- Ages 55+
- RecruitingPhase 3
Sarilumab Efficacy and Safety in Adults With Early Polymyalgia Rheumatica
Sanofi
- Location
- Avondale, AZ + 46 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2
A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)
Merck Sharp & Dohme LLC
- Location
- Irvine, CA + 34 other US sites
- Eligibility basics
- Ages 50–85
- RecruitingPhase 1/Phase 2
A Safety and Efficacy Study of a One-time Intravitreal Injection of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration
Sanofi
- Location
- Peoria, AZ + 30 other US sites
- Eligibility basics
- Ages 60+
- RecruitingPhase 2
Deep Sleep in Older Adults
Proactive Life Inc
- Location
- New York, NY
- Eligibility basics
- Ages 55+
- RecruitingPhase 2/Phase 3
ACP-204 in Adults With Alzheimer's Disease Psychosis
ACADIA Pharmaceuticals Inc.
- Location
- Scottsdale, AZ + 34 other US sites
- Eligibility basics
- Ages 55–95
- RecruitingPhase 3
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
Hoffmann-La Roche
- Location
- Birmingham, AL + 67 other US sites
- Eligibility basics
- Ages 50–90
- RecruitingPhase 4
A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)
Alpha Cognition, Inc
- Location
- Irvine, CA + 21 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- Location
- Anaheim, CA + 56 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 3
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- Location
- Stuart, FL + 2 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 3
A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)
Bristol-Myers Squibb
- Location
- Scottsdale, AZ + 10 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 1/Phase 2
An Optimised GA Interventional Trial (Opti-GAIN) to Test if Treatment With CTx001 is Safe and Works for People With Geographic Atrophy (GA)
Complement Therapeutics
- Location
- Carmel, IN + 3 other US sites
- Eligibility basics
- Ages 55+
- RecruitingPhase 3
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)
Bristol-Myers Squibb
- Location
- Scottsdale, AZ + 21 other US sites
- Eligibility basics
- Ages 55–90
Questions
If I fit this group, will I qualify?
Not necessarily. Age and sex limits are only the first filter. Each study has its own inclusion and exclusion criteria, and the research team decides at screening.
Where do these age and sex limits come from?
From the eligibility section of each study’s official ClinicalTrials.gov record. We don’t infer eligibility from anything else.