Phase 1 · San Diego area, CA
Phase 1 clinical trials in San Diego area, CA
47 recruiting studies have a site in the San Diego area. This page includes nearby cities such as La Jolla, Chula Vista, Escondido, Oceanside.
47 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 1
A Study to Assess Sulbactam-durlobactam in Pediatric Patients With Acinetobacter Baumannii-calcoaceticus Complex Infection
Innoviva Specialty Therapeutics
- Location
- Los Angeles, CA + 3 other US sites
- Eligibility basics
- Ages 0 mo–18
- RecruitingPhase 1
A Study to Evaluate the Efficacy and Safety of Cannabidiol Oral Solution (CBD-OS [GWP42003-P, JZP926]) for the Treatment of Focal-Onset Seizures
Jazz Pharmaceuticals
- Location
- La Jolla, CA + 20 other US sites
- Eligibility basics
- Ages 12–75
- RecruitingPhase 1
A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy
Rocket Pharmaceuticals Inc.
- Location
- San Diego, CA + 2 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1
A Study to Investigate the Safety and Pharmacodynamics of a Single Intrathecal Injection (IT) of INS1202 in Participants With Amyotrophic Lateral Sclerosis (ALS)
Insmed Gene Therapy LLC
- Location
- La Jolla, CA + 6 other US sites
- Eligibility basics
- Ages 18–79
- RecruitingPhase 1/Phase 2
Treatment of Participants With Primary or Secondary Progressive Multiple Sclerosis
Tr1X, Inc.
- Location
- La Jolla, CA + 7 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1
A Gene Transfer Therapy Study to Evaluate the Safety of and Expression From Delandistrogene Moxeparvovec (SRP-9001) in Participants With Duchenne Muscular Dystrophy (DMD) - Non-Ambulatory Cohort
Sarepta Therapeutics, Inc.
- Location
- La Jolla, CA + 10 other US sites
- Eligibility basics
- Ages 2+ · Men only
- RecruitingPhase 1/Phase 2
CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)
COUR Pharmaceutical Development Company, Inc.
- Location
- Newport Beach, CA + 44 other US sites
- Eligibility basics
- Ages 12–35
- RecruitingPhase 1
A Study to Assess the Safety and Clinical Activity of Azer-cel in Participants With B-cell Mediated Autoimmune Disorders
TG Therapeutics, Inc.
- Location
- La Jolla, CA + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Study to Evaluate Sequential Administration of Injections of AGN-151586 Followed by BOTOX in Adult Participants for Treatment of Glabellar Lines
AbbVie
- Location
- Newport Beach, CA + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
Study Assessing CLENPIQ as Bowel Preparation for Pediatric Colonoscopy
Ferring Pharmaceuticals
- Location
- San Diego, CA + 3 other US sites
- Eligibility basics
- Ages 1–8
- RecruitingPhase 1/Phase 2
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne
Sanofi Pasteur, a Sanofi Company
- Location
- Cerritos, CA + 78 other US sites
- Eligibility basics
- Ages 18–45
- RecruitingPhase 1/Phase 2
A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants, Adolescents and Adults With Hearing Loss Due to Otoferlin Mutations
Regeneron Pharmaceuticals
- Location
- Los Angeles, CA + 8 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 1/Phase 2
A Study of SGT-003 Gene Therapy in Duchenne Muscular Dystrophy (INSPIRE DUCHENNE)
Solid Biosciences Inc.
- Location
- Los Angeles, CA + 11 other US sites
- Eligibility basics
- Ages 0 mo–17 · Men only
- RecruitingPhase 1
A Study on the Safety and Immune Response of Investigational mRNA Seasonal Flu/COVID-19 Combination Vaccine in Adults
GlaxoSmithKline
- Location
- Fair Oaks, CA + 11 other US sites
- Eligibility basics
- Ages 65–85
- RecruitingPhase 1
R-2487 in Patients With Rheumatoid Arthritis
Rise Therapeutics LLC
- Location
- San Diego, CA + 5 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
A Single Bolus, 12-hour Euglycemic Clamp Study of the Safety, Pharmacokinetics (PK) and Glucodynamics (GD) of Intraperitoneal (IP) Portal Insulin U-500
Portal Diabetes, Inc.
- Location
- Chula Vista, CA
- Eligibility basics
- Ages 18–60
- RecruitingPhase 1
A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)
Rocket Pharmaceuticals Inc.
- Location
- La Jolla, CA + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis
Amylyx Pharmaceuticals Inc.
- Location
- La Jolla, CA + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM
Tenaya Therapeutics
- Location
- La Jolla, CA + 4 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
A Study to Evaluate the Safety of a Delivery Device for Administering LCTOPC1 in Participants With Spinal Cord Injury
Lineage Cell Therapeutics, Inc.
- Location
- La Jolla, CA
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1/Phase 2
A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)
Neurona Therapeutics
- Location
- Los Angeles, CA + 15 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
An Extension Study to Evaluate the Long-Term Safety and Clinical Activity of mRNA-3705 in Participants Previously Enrolled in Other Clinical Studies of mRNA-3705
ModernaTX, Inc.
- Location
- Los Angeles, CA + 2 other US sites
- Eligibility basics
- Ages 1+
- RecruitingPhase 1/Phase 2
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction
Sardocor Corp.
- Location
- San Diego, CA + 4 other US sites
- Eligibility basics
- Ages 18–80
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.