Phase 1 · San Francisco area, CA
Phase 1 clinical trials in San Francisco area, CA
83 recruiting studies have a site in the San Francisco area. This page includes nearby cities such as Oakland, Berkeley, San Mateo, Palo Alto.
83 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1/Phase 2
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
Xencor, Inc.
- Location
- Palo Alto, CA + 27 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1
A Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of BCX17725
BioCryst Pharmaceuticals
- Location
- Palo Alto, CA + 4 other US sites
- Eligibility basics
- Ages 12–65
- RecruitingHealthy volunteersEarly Phase 1
Radiocaine Safety Study
Lutroo Imaging LLC
- Location
- Stanford, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease
Bristol-Myers Squibb
- Location
- La Jolla, CA + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Novartis Pharmaceuticals
- Location
- Orange, CA + 18 other US sites
- Eligibility basics
- Ages 18–100
- RecruitingHealthy volunteersPhase 1
A Study to Learn About a Vaccine Against E Coli in Healthy Adults
Pfizer
- Location
- Anaheim, CA + 9 other US sites
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteersPhase 1
A 3-part Study of SYX-5219 in Healthy Volunteers and Participants With Atopic Dermatitis
Sitryx Therapeutics Ltd
- Location
- Fremont, CA + 5 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1/Phase 2
Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers
Ashvattha Therapeutics, Inc.
- Location
- San Francisco, CA + 2 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1/Phase 2
Spermatogonial Differentiation Via Testicular Organoid
CellARTs Inc.
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18–60 · Men only
- RecruitingPhase 1Overnight stay mentioned
A Study of GNTI-122 in Adults Recently Diagnosed With T1D
GentiBio, Inc
- Location
- Duarte, CA + 8 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
Safety Study of MucoCept-CVN
Craig Cohen, MD, MPH
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18–45 · Women only
- RecruitingHealthy volunteersPhase 1
Inflammatory Challenge and Fear
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- San Francisco, CA + 3 other US sites
- Eligibility basics
- Ages 18–60
- RecruitingHealthy volunteersPhase 1
Safety and Tolerability Trial of Psilocybin in Healthy Older Adults
University of Colorado, Denver
- Location
- San Francisco, CA + 5 other US sites
- Eligibility basics
- Ages 65–85
- RecruitingHealthy volunteersPhase 1
A Study of Psychedelics in Healthy Older Adults With Low Well-being
Jennifer Mitchell
- Location
- San Francisco, CA
- Eligibility basics
- Ages 50–85
- RecruitingHealthy volunteersEarly Phase 1
Randomized Directly Observed Therapy Study to Interpret Clinical Trials of Doxy-PEP
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- San Francisco, CA + 4 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
Dopamine and Sensorimotor Function in Stuttering
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1/Phase 2
A Phase 1/2A, Randomized Study of a T Follicular Helper (TFH)-Targeting Genetic Vaccine Strategy Designed to Induce Broad, Durable Immune Responses
Kara Chew
- Location
- Los Angeles, CA + 1 other US site
- Eligibility basics
- Ages 40–64
- RecruitingHealthy volunteersPhase 1
Investigating the Mechanisms of the Effects of Psilocybin on Visual Perception and Visual Representations in the Brain
University of California, Berkeley
- Location
- Berkeley, CA
- Eligibility basics
- Ages 21+
- RecruitingHealthy volunteersEarly Phase 1
Multiparametric [18F]F-AraG Imaging in Post-Acute Sequelae of COVID-19 (PASC)
University of California, Davis
- Location
- Sacramento, CA + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 21–65
- RecruitingHealthy volunteersPhase 1/Phase 2
FACE Phase II (a Stage II Trial)
Stanford University
- Location
- Palo Alto, CA
- Eligibility basics
- Ages 60–89
- RecruitingHealthy volunteersEarly Phase 1
Statin Therapy in Primary Sclerosing Cholangitis (PSC): a Multi-omics Study
Stanford University
- Location
- Stanford, CA
- Eligibility basics
- Ages 18–80
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.