Phase 1 · San Francisco area, CA
Phase 1 clinical trials in San Francisco area, CA
83 recruiting studies have a site in the San Francisco area. This page includes nearby cities such as Oakland, Berkeley, San Mateo, Palo Alto.
83 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1
PET Imaging Study of 64Cu-GRIP B for Patients Receiving CD19-directed CAR-T Therapy
Michael Randall
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersEarly Phase 1
Precision Dosing of Metformin in Youth With T2D
University of California, San Francisco
- Location
- Oakland, CA + 1 other US site
- Eligibility basics
- Ages 10–21
- RecruitingHealthy volunteersPhase 1
Investigating the Persisting Effects of a Single Dose of Psilocybin on Structural Plasticity in Healthy Older Adults
University of California, Berkeley
- Location
- Berkeley, CA
- Eligibility basics
- Ages 60–85
- RecruitingHealthy volunteersPhase 1
PET Imaging of Radiolabeled Anti-HIV-1 Envelope Monoclonal Antibody (VRC01)
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1/Phase 2
First-in-Human Evaluation of an Astrocytic Glutamate Transporter (EAAT2) PET Tracer in Dementia
David Wilson
- Location
- San Francisco, CA
- Eligibility basics
- Ages 40–75
- RecruitingHealthy volunteersPhase 1
Imaging Synapses With [11C] UCB-J in the Human Brain
Davidzon, Guido, M.D.
- Location
- Palo Alto, CA + 1 other US site
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
CogT pSOPT Intervention Study
Stanford University
- Location
- Palo Alto, CA
- Eligibility basics
- Ages 60+
- RecruitingPhase 1/Phase 2
A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome
Encoded Therapeutics
- Location
- San Francisco, CA + 9 other US sites
- Eligibility basics
- Ages 6 mo–17
- RecruitingPhase 1
A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease
CRISPR Therapeutics
- Location
- La Jolla, CA + 7 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1/Phase 2
A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia B
Regeneron Pharmaceuticals
- Location
- Los Angeles, CA + 16 other US sites
- Eligibility basics
- Ages 2+ · Men only
- RecruitingPhase 1
Safety and Preliminary Efficacy of ULSC in Facioscapulohumeral Muscular Dystrophy (FSHD)
Restem, LLC.
- Location
- Palo Alto, CA
- Eligibility basics
- Ages 15+
- RecruitingPhase 1/Phase 2
A Safety and Efficacy Study of a One-time Intravitreal Injection of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration
Sanofi
- Location
- Beverly Hills, CA + 30 other US sites
- Eligibility basics
- Ages 60+
- RecruitingPhase 1/Phase 2
RESET-MG: A Study to Evaluate the Safety and Efficacy of CABA-201 in Participants With Generalized Myasthenia Gravis
Cabaletta Bio
- Location
- Orange, CA + 16 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1
Study of KITE-363 in Participants With Autoimmune Neurologic Diseases That Did Not Respond to Usual Treatment
Kite, A Gilead Company
- Location
- Newport Beach, CA + 4 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events
Novo Nordisk A/S
- Location
- Walnut Creek, CA + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
DFT383 in Pediatric Participants With Nephropathic Cystinosis
Novartis Pharmaceuticals
- Location
- San Diego, CA + 5 other US sites
- Eligibility basics
- Ages 2–5
- RecruitingPhase 1
Obe-cel in Refractory Progressive Forms of Multiple Sclerosis
Autolus Limited
- Location
- Palo Alto, CA
- Eligibility basics
- Ages 18–60
- RecruitingPhase 1/Phase 2
A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With…
Cabaletta Bio
- Location
- Redwood City, CA + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated
Boehringer Ingelheim
- Location
- Arcadia, CA + 24 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Clinical Study of Letermovir (MK-8228) in Children and Adolescents Who Receive a Kidney Transplant (KT) (MK-8228-077)
Merck Sharp & Dohme LLC
- Location
- Los Angeles, CA + 20 other US sites
- Eligibility basics
- Up to age 17
- RecruitingPhase 1/Phase 2
A Gene Therapy Study of SPK-8011QQ in Adults With Severe or Moderately Severe Hemophilia A
Hoffmann-La Roche
- Location
- Orange, CA + 5 other US sites
- Eligibility basics
- Ages 18+ · Men only
- RecruitingPhase 1
A Phase 1 Study of LY5830966 in Participants With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I…
Ajax Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company
- Location
- Palo Alto, CA + 12 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Trial to Test the Safety and Efficacy of TEV-53408 in Participants With Vitiligo
Teva Branded Pharmaceutical Products R&D LLC
- Location
- Fremont, CA + 2 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
A Study of Pirtobrutinib in Participants With Immune Thrombocytopenia
Eli Lilly and Company
- Location
- Los Angeles, CA + 7 other US sites
- Eligibility basics
- Ages 18+
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.